Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 20/20 | 0.68 |
| ▸ | ABCC8 | Q09428 | 20/20 | 0.68 |
| ▸ | KCNJ11 | Q14654 | 20/20 | 0.68 |
| ▸ | KCNJ8 | Q15842 | 20/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7833345 | 0.91 | ABCC9 (0.75) | ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL7836348 | 0.86 | ABCC9 (0.72) | ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL7832437 | 0.85 | GPR174 (0.59) | ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL6928469 | 0.83 | ABCC9 (0.64) | ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL7832048 | 0.83 | ABCC9 (0.56) | ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL7853122 | 0.82 | ABCC9 (0.77) | ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL6910292 | 0.82 | ABCC9 (0.63) | ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL6910087 | 0.82 | ABCC9 (0.63) | ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL7835588 | 0.81 | KDM4E (0.61) | ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL1002731 | 0.79 | ABCC9 (0.73) | ABCC9ABCC8KCNJ11KCNJ8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0665834-B1 | QUINOLONE AND ACRIDINONE DERIVATIVES FOR THE TREATMENT OF URINARY INCONTINENCE | ASTRAZENECA AB (SE) | 2001-05-30 | — | — | EP | disclosed |