Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.38 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.38 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7835197 | 0.88 | TSHR (0.46) | MEN1KMT2ALMNATSHRGRIN2B | |
| SCHEMBL7837273 | 0.86 | TSHR (0.45) | MEN1KMT2ALMNATSHRGRIN2B | |
| SCHEMBL6317736 | 0.81 | NPSR1 (0.49) | MEN1KMT2ALMNATSHRGRIN2B | |
| SCHEMBL7832340 | 0.81 | TSHR (0.48) | MEN1KMT2ALMNATSHRGRIN2B | |
| SCHEMBL7832805 | 0.80 | TSHR (0.62) | MEN1KMT2ALMNATSHRALDH1A1 | |
| SCHEMBL7838453 | 0.80 | ADRB2 (0.49) | MEN1KMT2ALMNATSHRGRIN2B | |
| SCHEMBL7832141 | 0.80 | NPSR1 (0.48) | MEN1KMT2ALMNATSHRGRIN2B | |
| SCHEMBL7837276 | 0.77 | TSHR (0.50) | MEN1KMT2ALMNATSHRGRIN2B | |
| SCHEMBL7832660 | 0.77 | ADRB2 (0.46) | MEN1KMT2ALMNATSHRGRIN2B | |
| SCHEMBL7823407 | 0.76 | TSHR (0.38) | MEN1KMT2ALMNATSHRGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1144415-A2 | FUNCTIONALIZED HETEROCYCLES AS CHEMOKINE RECEPTOR MODULATORS | WARNER-LAMBERT COMPANY (US) | 2001-10-17 | — | — | EP | disclosed |
| WO-2000042045-A2 | FUNCTIONALIZED HETEROCYCLES AS CHEMOKINE RECEPTOR MODULATORS | WARNER-LAMBERT COMPANY (US) | 2000-07-20 | — | — | WO | disclosed |