SCHEMBL7834812

SCHEMBL7834812

O=C1C=C=Nc2ccccc21

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 3/20 0.37
IDO1 P14902 3/20 0.37
CDC25B P30305 2/20 0.37
MAOB P27338 2/20 0.37
AKT1 P31749 1/20 0.37
SNCA P37840 1/20 0.37
MAP2K1 Q02750 1/20 0.37
PIN1 Q13526 1/20 0.37
EHMT2 Q96KQ7 1/20 0.37
NSD1 Q96L73 1/20 0.37
EHMT1 Q9H9B1 1/20 0.37
MEN1 O00255 4/20 0.35
KMT2A Q03164 4/20 0.35
KDM4E B2RXH2 3/20 0.33
LMNA P02545 3/20 0.33
MAPT P10636 3/20 0.33
APAF1 O14727 3/20 0.33
BCHE P06276 2/20 0.33
POLB P06746 2/20 0.33
PTPRC P08575 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9383620 0.74 MAOA (0.37) MAOAIDO1CDC25BMAOBAKT1
SCHEMBL182909 0.68 MEN1 (0.38) MAOAIDO1CDC25BMAOBAKT1
SCHEMBL1497963 0.65 CDC25B (0.42) MAOAIDO1CDC25BMAOBAKT1
SCHEMBL29409962 0.65 CDC25B (0.42) MAOAIDO1CDC25BMAOBAKT1
Hydrochloric Acid SCHEMBL10863150 0.64 KMT2A (0.40) MAOAIDO1CDC25BMAOBAKT1
Hydrochloric Acid SCHEMBL10860848 0.64 KMT2A (0.40) MAOAIDO1CDC25BMAOBAKT1
Potassium SCHEMBL31207020 0.64 KMT2A (0.40) MAOAIDO1CDC25BMAOBAKT1
Methane SCHEMBL28363844 0.64 KMT2A (0.40) MAOAIDO1CDC25BMAOBAKT1
SCHEMBL25254110 0.62 CDC25B (0.50) MAOAIDO1CDC25BMAOBAKT1
SCHEMBL20585012 0.62 CDC25B (0.39) MAOAIDO1CDC25BMAOBAKT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0710882-B1 Colour photographic material AGFA GEVAERT (BE) 2001-01-03 EP disclosed
CN-1252045-A Method for producing cleavage products from castor oil or derivatives thereof CASCHEM INC (US) 2000-05-03 CN disclosed
EP-0710882-A1 New yellow couplers of indolo 3,2-b quinolin-type and their use in a colour photographic developing process Agfa-Gevaert AG (DE) 1996-05-08 EP disclosed
EP-0143018-B1 PROCESS FOR THE PREPARATION OF 4-QUINOLINONES RHONE-POULENC SANTE (FR) 1987-09-02 EP disclosed
EP-0140748-B1 PROCESS FOR THE PREPARATION OF 4-QUINOLINONES RHONE-POULENC SANTE (FR) 1987-01-14 EP disclosed
EP-0143018-A1 Process for the preparation of 4-quinolinones RHONE-POULENC SANTE (FR) 1985-05-29 EP disclosed
EP-0140748-A1 Process for the preparation of 4-quinolinones RHONE-POULENC SANTE (FR) 1985-05-08 EP disclosed
EP-0056763-B1 PROCESS FOR THE PREPARATION OF 4-QUINOLINONES RHONE-POULENC SANTE (FR) 1984-07-04 EP disclosed
EP-0056763-A2 Process for the preparation of 4-quinolinones RHONE-POULENC SANTE (FR) 1982-07-28 EP disclosed