Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 19/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 19/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | PLG | P00747 | 1/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.45 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.45 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.45 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7837038 | 0.94 | ITGB3 (0.53) | ITGB3ITGA2BF2PLGPRSS1 | |
| SCHEMBL7835873 | 0.88 | YAP1 (0.41) | PRSS1 | |
| SCHEMBL7834876 | 0.88 | ITGB3 (0.60) | ITGB3ITGA2B | |
| SCHEMBL7833863 | 0.86 | ITGB3 (0.51) | ITGB3ITGA2BF2PLGPRSS1 | |
| SCHEMBL7824915 | 0.86 | ITGB3 (0.55) | ITGB3ITGA2B | |
| SCHEMBL7835813 | 0.85 | ITGB3 (0.51) | ITGB3ITGA2BF2PLGPRSS1 | |
| SCHEMBL7826447 | 0.83 | ITGB3 (0.56) | ITGB3ITGA2BTPSAB1 | |
| SCHEMBL7838327 | 0.83 | ITGB3 (0.48) | ITGB3ITGA2BF2PLGPRSS1 | |
| SCHEMBL7834526 | 0.83 | ITGB3 (0.53) | ITGB3ITGA2BF2PLGPRSS1 | |
| SCHEMBL7836339 | 0.82 | YAP1 (0.44) | ITGB3ITGA2BPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0800516-B1 | FIBRINOGEN RECEPTOR ANTAGONISTS HAVING SUBSTITUTED (b)-AMINO ACID RESIDUES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | NIPPON STEEL CORP (JP) | 2001-09-19 | — | — | EP | disclosed |
| US-5866592-A | Fibrinogen receptor antagonist and pharmaceutical compositions comprising the same | NIPPON STEEL CORPORATION (JP) | 1999-02-02 | — | — | US | disclosed |