SCHEMBL7835129

SCHEMBL7835129

Cc1n[nH]c(=O)n1C(F)F

nearest known ligand 0.40

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.40
L3MBTL1 Q9Y468 2/20 0.37
POLB P06746 1/20 0.37
TSHR P16473 1/20 0.35
CYP1A2 P05177 2/20 0.35
CYP2C9 P11712 1/20 0.34
NPC1 O15118 1/20 0.30
RAB9A P51151 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3524639 0.80 TDP1 (0.44) TDP1L3MBTL1POLBTSHRCYP1A2
SCHEMBL8799184 0.74 CYP2C9 (0.32) TDP1CYP1A2CYP2C9
SCHEMBL12692985 0.70 TDP1 (0.41) TDP1L3MBTL1POLBTSHRCYP1A2
SCHEMBL8883068 0.70 LMNA (0.30)
SCHEMBL17380639 0.68 GAA (0.38) RAB9A
SCHEMBL762702 0.67
SCHEMBL13948815 0.65
SCHEMBL8786920 0.63 TDP1 (0.41) TDP1L3MBTL1POLBTSHRCYP1A2
SCHEMBL8621897 0.62
SCHEMBL13216885 0.62 PPOX (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109776437-B Preparation method of sulfentrazone 江苏中旗科技股份有限公司 2022-02-25 CN claimed
EP-0656892-B1 HERBICIDAL 2- (4-HETEROCYCLIC-PHENOXYMETHYL)PHENOXY]-ALKANOATES FMC CORP (US) 2001-06-13 EP claimed
CN-109776437-B Preparation method of sulfentrazone 江苏中旗科技股份有限公司 2022-02-25 CN disclosed
CN-109796419-B Preparation method of sulfentrazone through catalytic coupling of copper reagent 江苏中旗科技股份有限公司 2022-01-21 CN disclosed
CN-106478532-A A kind of method of synthesis sulfentrazone 江苏瑞邦农药厂有限公司 2017-03-08 CN disclosed
US-7488824-B2 Process for the production of substituted nicotinic acid esters SYNGENTA CROP PROTECTION, INC. (US) 2009-02-10 US disclosed
US-7488824-B2 Process for the production of substituted nicotinic acid esters SYNGENTA CROP PROTECTION, INC. (US) 2009-02-10 US disclosed
EP-1601653-B1 PROCESS FOR THE PRODUCTION OF SUBSTITUTED NICOTINIC ACID ESTERS SYNGENTA PARTICIPATIONS AG (CH) 2009-02-04 EP disclosed
EP-0656892-B1 HERBICIDAL 2- (4-HETEROCYCLIC-PHENOXYMETHYL)PHENOXY]-ALKANOATES FMC CORP (US) 2001-06-13 EP disclosed
US-5468868-A Process for the selective chlorination of 4,5-dihydro-1-phenyl-1H-1,2,4-triazol-5-one FMC CORPORATION (US) 1995-11-21 US disclosed