Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | HRH2 | P25021 | 1/20 | 0.38 |
| ▸ | PTAFR | P25105 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7847458 | 0.99 | CNR1 (0.42) | CNR1HRH2PTAFR | |
| SCHEMBL7847829 | 0.84 | — | — | |
| Hydrochloric Acid SCHEMBL7843012 | 0.83 | — | — | |
| SCHEMBL7846036 | 0.83 | — | — | |
| SCHEMBL7836609 | 0.81 | MAPK14 (0.40) | — | |
| SCHEMBL7844030 | 0.80 | P2RX7 (0.38) | — | |
| Hydrochloric Acid SCHEMBL7847822 | 0.80 | P2RX7 (0.38) | CNR1 | |
| SCHEMBL7842644 | 0.73 | CNR2 (0.37) | PTAFR | |
| SCHEMBL7497278 | 0.73 | — | — | |
| SCHEMBL7849083 | 0.73 | PTGER4 (0.40) | PTAFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0821685-B1 | INDOLE-3-CARBONYL AND INDOLE-3-SULFONYL DERIVATIVES AS PLATELET ACTIVATING FACTOR ANTAGONISTS | ABBOTT LAB (US) | 2001-10-04 | — | — | EP | claimed |
| EP-0821685-A1 | INDOLE-3-CARBONYL AND INDOLE-3-SULFONYL DERIVATIVES AS PLATELET ACTIVATING FACTOR ANTAGONISTS | ABBOTT LABORATORIES (US) | 1998-02-04 | — | — | EP | claimed |
| WO-1996033196-A1 | INDOLE-3-CARBONYL AND INDOLE-3-SULFONYL DERIVATIVES AS PLATELET ACTIVATING FACTOR ANTAGONISTS | ABBOTT LABORATORIES (US) | 1996-10-24 | — | — | WO | claimed |
| US-5567711-A | Indole-3-carbonyl and indole-3-sulfonyl derivatives as platelet activating factor antagonists | ABBOTT LABORATORIES (US) | 1996-10-22 | — | — | US | claimed |
| EP-0821685-B1 | INDOLE-3-CARBONYL AND INDOLE-3-SULFONYL DERIVATIVES AS PLATELET ACTIVATING FACTOR ANTAGONISTS | ABBOTT LAB (US) | 2001-10-04 | — | — | EP | disclosed |
| WO-1996033196-A1 | INDOLE-3-CARBONYL AND INDOLE-3-SULFONYL DERIVATIVES AS PLATELET ACTIVATING FACTOR ANTAGONISTS | ABBOTT LABORATORIES (US) | 1996-10-24 | — | — | WO | disclosed |
| US-5567711-A | Indole-3-carbonyl and indole-3-sulfonyl derivatives as platelet activating factor antagonists | ABBOTT LABORATORIES (US) | 1996-10-22 | — | — | US | disclosed |