SCHEMBL7835360

SCHEMBL7835360

O=c1c(Cl)c(S)sc2ccsc12.[NaH]

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GPR35 Q9HC97 1/20 0.35
PDPK1 O15530 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7834183 0.79 GPR35 (0.39) GPR35
SCHEMBL7775858 0.76 GPR35 (0.40) GPR35
SCHEMBL7830917 0.72 GPR35 (0.33) GPR35PDPK1
SCHEMBL7831530 0.70 GPR35 (0.32) GPR35
SCHEMBL7774037 0.68 GPR35 (0.38) GPR35PDPK1
SCHEMBL407079 0.63 GPR35 (0.46) GPR35
SCHEMBL5041374 0.63 GPR35 (0.44) GPR35
SCHEMBL22831733 0.63 GPR3 (0.48) GPR35
SCHEMBL1158425 0.61 GPR35 (0.45) GPR35
SCHEMBL12688138 0.60 GPR35 (0.43) GPR35

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1090920-A1 CEPHEM COMPOUNDS ZENYAKU KOGYO KABUSHIKI KAISHA (JP) 2001-04-11 EP disclosed