SCHEMBL783558

SCHEMBL783558

OCCCCc1ccc2c(c1)CCc1cc(O)ccc1-2

nearest known ligand 0.49

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
AKR1B1 P15121 2/20 0.49
IGF1R P08069 2/20 0.42
ALOX15 P16050 2/20 0.42
CYP26A1 O43174 4/20 0.41
BCHE P06276 5/20 0.40
ACHE P22303 2/20 0.40
MAOA P21397 1/20 0.40
MAOB P27338 1/20 0.40
PRKCI P41743 1/20 0.40
ALOX5 P09917 1/20 0.40
HSP90AA1 P07900 1/20 0.40
SLC28A3 Q9HAS3 1/20 0.38
GRIN2B Q13224 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9145294 0.84 SRD5A1 (0.45) IGF1RALOX15BCHEACHEHSP90AA1
SCHEMBL5683877 0.80 AKR1B1 (0.51) AKR1B1ALOX15CYP26A1MAOAMAOB
SCHEMBL22369581 0.79 GRIN2B (0.44) IGF1RALOX15BCHEACHEGRIN2B
SCHEMBL784291 0.76 MAOB (0.59) AKR1B1CYP26A1MAOAMAOBPRKCI
SCHEMBL4942353 0.76 PTGS2 (0.54) ALOX15ACHEALOX5
SCHEMBL1698287 0.76 PTGS2 (0.41) BCHEACHEGRIN2B
SCHEMBL3531737 0.75 GAA (0.45) IGF1RALOX15BCHEACHEALOX5
SCHEMBL86398 0.75 CASP1 (0.47) AKR1B1MAOAMAOBPRKCI
SCHEMBL2311686 0.74 GPR84 (0.51) BCHEMAOA
SCHEMBL19190371 0.74 IGF1R (0.58) IGF1RALOX15ACHESLC28A3GRIN2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103627404-B Liquid-crystal display MERCK PATENT GMBH (DE) 2015-10-28 CN disclosed
CN-102439114-B Liquid crystal display device with a light guide plate MERCK PATENT GMBH (DE) 2015-08-26 CN disclosed
US-9096795-B2 Liquid crystal display MERCK PATENT GMBH (DE) 2015-08-04 US disclosed
US-9096795-B2 Liquid crystal display MERCK PATENT GMBH (DE) 2015-08-04 US disclosed
US-9096795-B2 Liquid crystal display MERCK PATENT GMBH (DE) 2015-08-04 US disclosed
CN-103627404-A Liquid crystal display MERCK PATENT GMBH 2014-03-12 CN disclosed
CN-103525430-A Liquid crystal display MERCK PATENT GMBH 2014-01-22 CN disclosed
EP-2432851-B1 LIQUID CRYSTAL DISPLAY MERCK PATENT GMBH (DE) 2013-10-02 EP disclosed
EP-2432851-B1 LIQUID CRYSTAL DISPLAY MERCK PATENT GMBH (DE) 2013-10-02 EP disclosed
CN-102439114-A Liquid crystal display device with a light guide plate MERCK PATENT GMBH 2012-05-02 CN disclosed
EP-2432851-A1 LIQUID CRYSTAL DISPLAY Merck Patent GmbH (DE) 2012-03-28 EP disclosed
US-20120069289-A1 LIQUID CRYSTAL DISPLAY MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2012-03-22 US disclosed
US-20120069289-A1 LIQUID CRYSTAL DISPLAY MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2012-03-22 US disclosed
US-20120069289-A1 LIQUID CRYSTAL DISPLAY MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2012-03-22 US disclosed
WO-2010133278-A1 LIQUID CRYSTAL DISPLAY MERCK PATENT GMBH (DE) 2010-11-25 WO disclosed
WO-2010133278-A1 LIQUID CRYSTAL DISPLAY MERCK PATENT GMBH (DE) 2010-11-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120069289-A1 LIQUID CRYSTAL DISPLAY LPXN, VCL, ACP3 AKR1B1 3961/4885IGF1R 4526/4885ALOX15 3558/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.