Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | ULK1 | O75385 | 1/20 | 0.51 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.50 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3711850 | 0.83 | L3MBTL1 (0.49) | RAB9APOLBL3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL2376784 | 0.83 | RAB9A (0.55) | RAB9APOLBL3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL5203429 | 0.82 | SHMT2 (0.56) | RAB9APOLBL3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL5396991 | 0.82 | MEN1 (0.53) | RAB9APOLBALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL3910980 | 0.82 | L3MBTL1 (0.59) | RAB9APOLBL3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL1581188 | 0.81 | L3MBTL1 (0.48) | RAB9APOLBL3MBTL1MEN1KMT2A | |
| SCHEMBL23958512 | 0.79 | CHRM2 (0.56) | RAB9AALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL3910280 | 0.76 | L3MBTL1 (0.73) | RAB9AL3MBTL1ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL12835536 | 0.76 | FERMT2 (0.54) | RAB9APOLBALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL30046801 | 0.76 | SHMT2 (0.45) | RAB9APOLBALDH1A1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0582789-B1 | Novel 7-(substituted)-8-(substituted)-9-(substituted glycyl)amido-6-demethyl-6-deoxytetracyclines | AMERICAN CYANAMID CO (US) | 2001-10-04 | — | — | EP | claimed |
| EP-0582789-B1 | Novel 7-(substituted)-8-(substituted)-9-(substituted glycyl)amido-6-demethyl-6-deoxytetracyclines | AMERICAN CYANAMID CO (US) | 2001-10-04 | — | — | EP | disclosed |