Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 5/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 5/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7843172 | 0.92 | GABRA1 (0.40) | GABRA1GABRB2GABRB1GABRA3 | |
| SCHEMBL7843284 | 0.86 | ALDH1A1 (0.33) | GABRA1GABRB2GABRB1GABRA3 | |
| SCHEMBL7843694 | 0.86 | GAA (0.46) | GABRA1GABRB2 | |
| SCHEMBL7845109 | 0.84 | CFTR (0.42) | GABRA1GABRB2GABRB1GABRA3 | |
| SCHEMBL7860741 | 0.83 | GABRA1 (0.39) | GABRA1GABRB2 | |
| SCHEMBL6670139 | 0.83 | CFTR (0.39) | GABRA1GABRB2 | |
| SCHEMBL7842246 | 0.83 | KDM4E (0.44) | GABRA1GABRB2 | |
| SCHEMBL7833923 | 0.82 | CFTR (0.45) | GABRA1GABRB2 | |
| SCHEMBL7847436 | 0.82 | KDM4E (0.44) | GABRA1GABRB2 | |
| SCHEMBL7845162 | 0.81 | GABRA1 (0.39) | GABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140850-A1 | QUINOLINECARBOXAMIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 2001-10-10 | — | — | EP | claimed |
| WO-2000040561-A1 | QUINOLINECARBOXAMIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 2000-07-13 | — | — | WO | claimed |