Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.55 |
| ▸ | CBFB | Q13951 | 1/20 | 0.53 |
| ▸ | F9 | P00740 | 6/20 | 0.49 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.47 |
| ▸ | FLT1 | P17948 | 1/20 | 0.47 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8148424 | 0.99 | SMN1; SMN2 (0.61) | SMN1; SMN2CYP4Z1CBFBF9FGFR1 | |
| SCHEMBL7836354 | 0.92 | CYP4Z1 (0.55) | SMN1; SMN2CYP4Z1CBFBF9MAPK10 | |
| Hydrochloric Acid SCHEMBL8148418 | 0.91 | CYP4Z1 (0.54) | SMN1; SMN2CYP4Z1CBFBF9MAPK10 | |
| SCHEMBL7834081 | 0.83 | HDAC6 (0.48) | SMN1; SMN2CYP4Z1CBFBF9FGFR1 | |
| SCHEMBL7822772 | 0.82 | CBFB (0.55) | CBFBF9FGFR1FLT1TSHR | |
| SCHEMBL7822350 | 0.80 | ALDH1A1 (0.50) | SMN1; SMN2CBFBF9FGFR1FLT1 | |
| SCHEMBL7834266 | 0.80 | SMN1; SMN2 (0.50) | SMN1; SMN2CBFBF9FGFR1FLT1 | |
| Hydrochloric Acid SCHEMBL7837257 | 0.79 | SMN1; SMN2 (0.49) | SMN1; SMN2CBFBF9FGFR1FLT1 | |
| SCHEMBL7832665 | 0.77 | CBFB (0.49) | CYP4Z1CBFBF9FGFR1FLT1 | |
| SCHEMBL7834394 | 0.77 | ALDH1A1 (0.50) | CBFBF9ALDH1A1HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0894795-B1 | Benzimidazole, benzoxazole and benzothiazole derivatives, their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2001-06-06 | — | — | EP | disclosed |
| EP-0894795-A1 | Benzimidazole, benzoxazole and benzothiazole derivatives, their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1999-02-03 | — | — | EP | disclosed |