Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SCN3A | Q9NY46 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phthalylsulfacetamide SCHEMBL49529 | 0.84 | ALDH1A1 (0.66) | ALDH1A1MAPTL3MBTL1HTTPKM | |
| Phthalylsulfacetamide SCHEMBL3911720 | 0.83 | ALDH1A1 (0.65) | ALDH1A1MAPTL3MBTL1HTTPKM | |
| Sulfaloxic Acid SCHEMBL151073 | 0.71 | LMNA (0.56) | ALDH1A1MAPTCYP3A4PTGS1LMNA | |
| SCHEMBL27450474 | 0.71 | HSD17B10 (0.71) | ALDH1A1MAPTL3MBTL1HTTPKM | |
| SCHEMBL6225889 | 0.70 | ALDH1A1 (0.78) | ALDH1A1MAPTL3MBTL1HTTPKM | |
| SCHEMBL18132522 | 0.69 | ALDH1A1 (0.55) | ALDH1A1MAPTCYP3A4PTGS1LMNA | |
| SCHEMBL14291632 | 0.69 | ALDH1A1 (0.76) | ALDH1A1MAPTL3MBTL1CYP3A4LMNA | |
| SCHEMBL14607436 | 0.69 | ALDH1A1 (0.59) | ALDH1A1MAPTL3MBTL1HTTPKM | |
| SCHEMBL11649341 | 0.69 | ALDH1A1 (0.53) | ALDH1A1MAPTHTTCYP3A4KDM4E | |
| SCHEMBL18132514 | 0.68 | LMNA (0.72) | ALDH1A1MAPTL3MBTL1HTTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |