Phthalylsulfacetamide

Phthalylsulfacetamide

SCHEMBL49529

CC(=O)NS(=O)(=O)c1ccc(NC(=O)c2ccccc2C(=O)O)cc1

nearest known ligand 0.66

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.66
MAPT P10636 1/20 0.66
PKM P14618 1/20 0.62
HTT P42858 1/20 0.62
LMNA P02545 1/20 0.60
CYP3A4 P08684 1/20 0.60
PTGS1 P23219 1/20 0.60
SCN3A Q9NY46 5/20 0.59
TDP1 Q9NUW8 2/20 0.57
L3MBTL1 Q9Y468 1/20 0.57
MEN1 O00255 1/20 0.55
KMT2A Q03164 1/20 0.55
HSD17B10 Q99714 1/20 0.55
KDM4E B2RXH2 1/20 0.53
HPGD P15428 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phthalylsulfacetamide SCHEMBL3911720 0.99 ALDH1A1 (0.65) ALDH1A1MAPTPKMHTTLMNA
SCHEMBL27450474 0.84 HSD17B10 (0.71) ALDH1A1MAPTPKMHTTLMNA
Phthalylsulfacetamide SCHEMBL7836470 0.84 ALDH1A1 (0.53) ALDH1A1MAPTPKMHTTLMNA
SCHEMBL6225889 0.84 ALDH1A1 (0.78) ALDH1A1MAPTPKMHTTSCN3A
SCHEMBL14291632 0.82 ALDH1A1 (0.76) ALDH1A1MAPTLMNACYP3A4L3MBTL1
SCHEMBL14607436 0.82 ALDH1A1 (0.59) ALDH1A1MAPTPKMHTTLMNA
Sulfaloxic Acid SCHEMBL151073 0.82 LMNA (0.56) ALDH1A1MAPTLMNACYP3A4PTGS1
SCHEMBL12189487 0.81 ALDH1A1 (0.69) ALDH1A1MAPTLMNACYP3A4PTGS1
SCHEMBL12700342 0.81 ALDH1A1 (0.69) ALDH1A1LMNACYP3A4PTGS1TDP1
SCHEMBL18132522 0.80 ALDH1A1 (0.55) ALDH1A1MAPTLMNACYP3A4PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1783 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3829310-B1 AGROCHEMICAL COMPOSITION AND METHODS OF PREPARING AND USING THE SAME SPECIALTY OPERATIONS FRANCE (FR) 2025-06-25 EP claimed
US-20250099557-A1 ANTIBIOTIC PHARMACEUTICAL COMPOSITION CAPABLE OF SUBCUTANEOUS ADMINISTRATION SHANGHAI BAO PHARMACEUTICALS CO., LTD. (CN) 2025-03-27 US claimed
WO-2025032301-A1 METHOD FOR SPINNING AN ELASTIC YARN DECATHLON (FR) 2025-02-13 WO claimed
EP-4374848-A1 ANTIBIOTIC PHARMACEUTICAL COMPOSITION CAPABLE OF SUBCUTANEOUS ADMINISTRATION Shanghai Bao Pharmaceuticals Co., Ltd. (CN) 2024-05-29 EP claimed
US-20230346879-A1 COMPOSITIONS AND METHODS FOR COMBINATORIAL DRUG DISCOVERY IN NANOLITER DROPLETS MASSACHUSETTS INSTITUTE OF TECHNOLOGY 2023-11-02 US claimed
EP-2252144-B1 USE OF ESTER AMIDES AS SOLVENTS, ESTER AMIDES AS SUCH, AND METHOD FOR PREPARING ESTER AMIDES RHODIA OPERATIONS (FR) 2023-08-02 EP claimed
CN-113539369-B Optimized kraken2 algorithm and application thereof in second-generation sequencing 江苏先声医学诊断有限公司 2022-03-25 CN claimed
CN-113539369-A Optimized kraken2 algorithm and application thereof in second-generation sequencing 江苏先声医学诊断有限公司 2021-10-22 CN claimed
US-10449247-B2 Compositions and methods for enhancing immune response AVIVAGEN INC. (CA) 2019-10-22 US claimed
EP-2953624-B1 METHODS OF TREATING MICROBIAL INFECTIONS, INCLUDING MASTITIS LUODA PHARMA LTD (IE) 2019-08-21 EP claimed
WO-2000048636-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2000-08-24 WO claimed
EP-0786999-A4 COMBINATION METHOD FOR ACNE TREATMENT MERCK & CO INC (US) 1999-01-20 EP claimed
EP-0792371-A4 COMBINATION METHOD FOR ACNE TREATMENT MERCK & CO INC (US) 1998-12-30 EP claimed
EP-0792371-A1 COMBINATION METHOD FOR ACNE TREATMENT Merck & Co., Inc. (US) 1997-09-03 EP claimed
EP-0786999-A1 COMBINATION METHOD FOR ACNE TREATMENT Merck & Co., Inc. (US) 1997-08-06 EP claimed
EP-0741570-A1 METHOD FOR PREVENTING OR REDUCING PHOTOSENSITIVITY AND/OR PHOTOTOXICITY REACTIONS TO MEDICATIONS G.D. SEARLE & CO. (US) 1996-11-13 EP claimed
US-5543417-A 5 Alpha-reductase inhibitor and at least one of an antibacterial agent, a keratolytic agent or an anti-inflammatory agent MERCK & CO., INC. (US) 1996-08-06 US claimed
WO-1996012487-A1 COMBINATION METHOD FOR ACNE TREATMENT MERCK & CO., INC. (US) 1996-05-02 WO claimed
WO-1996012817-A1 COMBINATION METHOD FOR ACNE TREATMENT MERCK & CO., INC. (US) 1996-05-02 WO claimed
WO-1995020387-A1 METHOD FOR PREVENTING OR REDUCING PHOTOSENSITIVITY AND/OR PHOTOTOXICITY REACTIONS TO MEDICATIONS G.D. SEARLE & CO. (US) 1995-08-03 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230346879-A1 COMPOSITIONS AND METHODS FOR COMBINATORIAL DRUG DISCOVERY IN NANOLITER DROPLETS RAB5IF, CLTB, TBK1 ALDH1A1 3381/4885MAPT 1926/4885PKM 3779/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.