Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7843123 | 0.91 | APLNR (0.44) | APLNRPTGS2MMP8MMP13CA2 | |
| SCHEMBL7840012 | 0.80 | CA12 (0.33) | CA2CA9CA12ALDH1A1CYP3A4 | |
| SCHEMBL7760688 | 0.80 | CA2 (0.33) | CA2 | |
| SCHEMBL7839760 | 0.79 | TDP1 (0.43) | ALDH1A1TSHRSMN1; SMN2KMT2A | |
| SCHEMBL7840826 | 0.77 | PTGS2 (0.39) | APLNRPTGS2MMP8MMP13CA2 | |
| SCHEMBL7756139 | 0.73 | GAA (0.54) | APLNRCA2CA9CA12ALDH1A1 | |
| SCHEMBL7840702 | 0.73 | GAA (0.58) | APLNRCA2CA9CA12ALDH1A1 | |
| SCHEMBL2097207 | 0.72 | CA12 (0.44) | CA2CA9CA12ALDH1A1TP53 | |
| SCHEMBL7841062 | 0.70 | PTGS2 (0.41) | APLNRPTGS2MMP8MMP13CA2 | |
| SCHEMBL7843604 | 0.69 | POLB (0.35) | PTGS2CA2PTGS1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0675172-B1 | Water-solable azo compounds, process for their preparation and their use as dyestuffs | DYSTAR TEXTILFARBEN GMBH & CO (DE) | 2001-04-11 | — | — | EP | disclosed |
| US-5770709-A | BRILLIANT COLOR SHADES, GOOD FASTNESS DURING USE AT HIGH DEGREE OF FIXING | DYSTAR TEXTILFARBEN GMBH & CO DEUTSCHLAND KG (DE) | 1998-06-23 | — | — | US | disclosed |
| EP-0629667-B1 | Water-soluble fiber-reactive dyes, process for their preparation and the use thereof | HOECHST AG (DE) | 1998-02-25 | — | — | EP | disclosed |
| US-5539088-A | PROVIDE DYEINGS IN BRILLIANT SHADES WITH GOOD FASTNESS PROPERTIES AND HIGH DEGREE OF FIXATION | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-07-23 | — | — | US | disclosed |
| EP-0629667-A1 | Water-soluble fiber-reactive dyes, process for their preparation and the use thereof | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-12-21 | — | — | EP | disclosed |