Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADA | P00813 | 14/20 | 0.43 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | TYR | P14679 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7847893 | 0.93 | ADA (0.43) | ADAHTR2CHTR2AHTR2B | |
| SCHEMBL7850190 | 0.92 | ADA (0.43) | ADA | |
| SCHEMBL7848399 | 0.88 | ADA (0.54) | ADAHTR2A | |
| SCHEMBL7850266 | 0.88 | PTPRA (0.41) | ADA | |
| SCHEMBL7847420 | 0.88 | ADA (0.49) | ADA | |
| SCHEMBL7848925 | 0.85 | ADA (0.44) | ADA | |
| SCHEMBL6940660 | 0.83 | ADA (0.58) | ADA | |
| SCHEMBL7848923 | 0.81 | CYP1A2 (0.41) | ADA | |
| SCHEMBL7846263 | 0.81 | ADA (0.48) | ADAHTR2A | |
| SCHEMBL6935332 | 0.76 | ADA (0.57) | ADAHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1161429-A2 | HETEROCYCLIC COMPOUNDS AS ADENOSINE DEAMINASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-12-12 | — | — | EP | disclosed |
| WO-2000055155-A2 | HETEROCYCLIC COMPOUNDS AS ADENOSINE DEAMINASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-09-21 | — | — | WO | disclosed |