SCHEMBL7848925

SCHEMBL7848925

CC(C)(C)[Si](C)(C)OC[C@@H](CCc1c[nH]c2ccc(CO)cc12)n1cnc(C(N)=O)c1

nearest known ligand 0.44

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ADA P00813 18/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7847893 0.90 ADA (0.43) ADA
SCHEMBL7846263 0.87 ADA (0.48) ADA
SCHEMBL7836809 0.85 ADA (0.43) ADA
SCHEMBL7850190 0.85 ADA (0.43) ADA
SCHEMBL7850266 0.82 PTPRA (0.41) ADA
SCHEMBL7848399 0.82 ADA (0.54) ADA
SCHEMBL7847420 0.82 ADA (0.49) ADA
SCHEMBL6170281 0.78 ADA (0.56) ADA
SCHEMBL7848923 0.75 CYP1A2 (0.41) ADA
SCHEMBL6935332 0.75 ADA (0.57) ADA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1161429-A2 HETEROCYCLIC COMPOUNDS AS ADENOSINE DEAMINASE INHIBITORS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2001-12-12 EP disclosed
WO-2000055155-A2 HETEROCYCLIC COMPOUNDS AS ADENOSINE DEAMINASE INHIBITORS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2000-09-21 WO disclosed