Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | CTSG | P08311 | 4/20 | 0.51 |
| ▸ | CMA1 | P23946 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 4/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7838574 | 0.85 | KMT2A (0.58) | KMT2ANPC1RAB9ACTSGCMA1 | |
| SCHEMBL7826151 | 0.82 | NPC1 (0.71) | KMT2ANPC1RAB9ACTSGCMA1 | |
| SCHEMBL7837528 | 0.82 | TSHR (0.53) | KMT2ANPC1RAB9ACTSGCMA1 | |
| SCHEMBL7836516 | 0.80 | KMT2A (0.60) | KMT2ANPC1RAB9ACTSGCMA1 | |
| SCHEMBL7838341 | 0.79 | CTSG (0.51) | KMT2ANPC1RAB9ACTSGCMA1 | |
| SCHEMBL7837470 | 0.76 | CTSG (0.53) | KMT2ANPC1RAB9ACTSGCMA1 | |
| SCHEMBL7837364 | 0.76 | KMT2A (0.55) | KMT2ANPC1RAB9ACTSGCMA1 | |
| SCHEMBL7833371 | 0.75 | CTSG (0.54) | KMT2ANPC1RAB9ACTSGCMA1 | |
| SCHEMBL921684 | 0.71 | NPC1 (0.51) | KMT2ANPC1RAB9ACTSGCMA1 | |
| SCHEMBL10546674 | 0.71 | KDM4E (0.49) | KMT2ACTSGCMA1MEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0721944-B1 | IMIDAZOLIDINE DERIVATIVE AND USE THEREOF | SUNTORY LTD (JP) | 2001-01-17 | — | — | EP | disclosed |
| US-5691335-A | CARDIOVASCULAR DISORDERS | SUNTORY LIMITED (JP) | 1997-11-25 | — | — | US | disclosed |
| EP-0721944-A1 | IMIDAZOLIDINE DERIVATIVE AND USE THEREOF | SUNTORY LIMITED (JP) | 1996-07-17 | — | — | EP | disclosed |