Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.45 |
| ▸ | CTSG | P08311 | 2/20 | 0.44 |
| ▸ | CMA1 | P23946 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7826151 | 0.84 | NPC1 (0.71) | NPC1RAB9AKMT2AMEN1CTSG | |
| SCHEMBL7836895 | 0.82 | KMT2A (0.51) | TSHRNPC1RAB9AKMT2AMEN1 | |
| SCHEMBL7836516 | 0.81 | KMT2A (0.60) | NPC1RAB9AKMT2AMEN1HPGD | |
| SCHEMBL7837470 | 0.80 | CTSG (0.53) | NPC1RAB9AKMT2AMEN1CTSG | |
| SCHEMBL7838574 | 0.80 | KMT2A (0.58) | LMNANPC1RAB9AKMT2AMEN1 | |
| SCHEMBL7837364 | 0.80 | KMT2A (0.55) | TSHRNPC1RAB9AKMT2AMEN1 | |
| SCHEMBL7833371 | 0.79 | CTSG (0.54) | TSHRLMNANPC1RAB9AKMT2A | |
| SCHEMBL11577852 | 0.77 | BCHE (0.56) | TSHRLMNANPC1RAB9AKMT2A | |
| SCHEMBL7823718 | 0.75 | BCHE (0.48) | LMNANPC1RAB9AKMT2AMEN1 | |
| SCHEMBL921684 | 0.72 | NPC1 (0.51) | NPC1RAB9AKMT2AMEN1CTSG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0721944-B1 | IMIDAZOLIDINE DERIVATIVE AND USE THEREOF | SUNTORY LTD (JP) | 2001-01-17 | — | — | EP | disclosed |
| US-5691335-A | CARDIOVASCULAR DISORDERS | SUNTORY LIMITED (JP) | 1997-11-25 | — | — | US | disclosed |
| EP-0721944-A1 | IMIDAZOLIDINE DERIVATIVE AND USE THEREOF | SUNTORY LIMITED (JP) | 1996-07-17 | — | — | EP | disclosed |