Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 3/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.57 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.57 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | MGLL | Q99685 | 1/20 | 0.55 |
| ▸ | BRPF1 | P55201 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7812540 | 0.81 | MAPT (0.53) | ADORA2BADORA3ADORA2AADORA1SMN1; SMN2 | |
| SCHEMBL5339818 | 0.77 | NOTUM (0.57) | SMN1; SMN2TP53ALDH1A1MGLLRAB9A | |
| SCHEMBL6511478 | 0.75 | MGLL (0.47) | ADORA2BADORA3ADORA2AADORA1SMN1; SMN2 | |
| SCHEMBL6511479 | 0.75 | MGLL (0.47) | ADORA2BADORA3ADORA2AADORA1SMN1; SMN2 | |
| Benzyl Phenylcarbamate SCHEMBL1222943 | 0.74 | POLB (0.78) | SMN1; SMN2TP53ALDH1A1LMNAMGLL | |
| SCHEMBL30207797 | 0.74 | MGLL (0.65) | SMN1; SMN2TP53ALDH1A1LMNAHTT | |
| SCHEMBL4432278 | 0.74 | MGLL (0.65) | SMN1; SMN2TP53ALDH1A1LMNAHTT | |
| SCHEMBL4202829 | 0.74 | TP53 (0.52) | SMN1; SMN2TP53ALDH1A1LMNAMGLL | |
| SCHEMBL5852207 | 0.74 | POLB (0.68) | SMN1; SMN2TP53ALDH1A1MGLLRAB9A | |
| SCHEMBL27562443 | 0.74 | POLB (0.68) | SMN1; SMN2TP53ALDH1A1MGLLRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0738726-B1 | Heterobenzocyclopentane oxazolidinones having antibacterial activity | BAYER AG (DE) | 2001-09-26 | — | — | EP | disclosed |
| CN-1138582-A | heteroatom-comtaining benzocyclopentane-oxazolidinones | BAYER AG (DE) | 1996-12-25 | — | — | CN | disclosed |
| EP-0738726-A1 | Heterobenzocyclopentane oxazolidinones having antibacterial activity | BAYER AG (DE) | 1996-10-23 | — | — | EP | disclosed |