Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | MGLL | Q99685 | 2/20 | 0.51 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.51 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3386295 | 0.82 | ALDH1A1 (0.52) | TP53MAPTALDH1A1SMN1; SMN2POLB | |
| SCHEMBL9193611 | 0.81 | SLC6A2 (0.54) | TP53MAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL5336933 | 0.80 | ROCK2 (0.49) | TP53MAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL30207797 | 0.76 | MGLL (0.65) | TP53MAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL4432278 | 0.76 | MGLL (0.65) | TP53MAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL5339818 | 0.76 | NOTUM (0.57) | TP53MAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL2746902 | 0.74 | MGLL (0.62) | TP53MAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL7836906 | 0.74 | ADORA2B (0.57) | TP53MAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL21244774 | 0.73 | NPC1 (0.56) | NPC1RAB9AMEN1KMT2AMAOA | |
| SCHEMBL16942604 | 0.72 | POLB (0.62) | TP53MAPTNPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090149520-A1 | OXAZOLIDINONES CONTAINING OXINDOLES AS ANTIBACTERIAL AGENTS | PFIZER INC | 2009-06-11 | — | — | US | disclosed |
| EP-2004640-A1 | OXAZOLIDINONES CONTAINING OXINDOLES AS ANTIBACTERIAL AGENTS | Pfizer Products Inc. (US) | 2008-12-24 | — | — | EP | disclosed |
| WO-2007091147-A1 | OXAZOLIDINONES CONTAINING OXINDOLES AS ANTIBACTERIAL AGENTS | PFIZER PRODUCTS INC. (US) | 2007-08-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090149520-A1 | OXAZOLIDINONES CONTAINING OXINDOLES AS ANTIBACTERIAL AGENTS | OXA1L, MT-ND4L, IL4I1 | TP53 3885/4885MAPT 3936/4885NPC1 2334/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.