Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.56 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.55 |
| ▸ | MGLL | Q99685 | 2/20 | 0.52 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | EGFR | P00533 | 1/20 | 0.51 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5336933 | 0.85 | ROCK2 (0.49) | NPC1ALDH1A1MAPTRAB9AMGLL | |
| SCHEMBL6097584 | 0.82 | ROCK2 (0.48) | NPC1ALDH1A1MAPTRAB9AMGLL | |
| SCHEMBL16696385 | 0.80 | RAB9A (0.53) | NOTUMNPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL16686040 | 0.78 | NPC1 (0.63) | NOTUMNPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL29510910 | 0.78 | NPC1 (0.78) | NOTUMNPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL7836906 | 0.77 | ADORA2B (0.57) | NPC1ALDH1A1MAPTRAB9AMGLL | |
| SCHEMBL4432278 | 0.77 | MGLL (0.65) | NPC1ALDH1A1MAPTRAB9AMGLL | |
| SCHEMBL30207797 | 0.77 | MGLL (0.65) | NPC1ALDH1A1MAPTRAB9AMGLL | |
| SCHEMBL16406932 | 0.77 | NOTUM (0.54) | NOTUMNPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL4202829 | 0.76 | TP53 (0.52) | NPC1ALDH1A1MAPTRAB9AMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007088478-A1 | INDAZOLE OXAZOLIDINONES AS ANTIBACTERIAL AGENTS | PFIZER PRODUCTS INC. (US) | 2007-08-09 | — | — | WO | disclosed |