Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.41 |
| ▸ | MEN1 | O00255 | 6/20 | 0.41 |
| ▸ | DCTPP1 | Q9H773 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6491706 | 1.00 | KMT2A (0.41) | KMT2AMEN1DCTPP1POLBMAPT | |
| SCHEMBL6505656 | 0.89 | DCTPP1 (0.42) | KMT2AMEN1DCTPP1POLBMAPT | |
| SCHEMBL6298966 | 0.86 | KMT2A (0.51) | KMT2AMEN1DCTPP1POLBMAPT | |
| SCHEMBL6491865 | 0.84 | PTGS2 (0.43) | KMT2AMEN1MAPTALDH1A1LMNA | |
| SCHEMBL6299298 | 0.83 | SMN1; SMN2 (0.40) | KMT2APOLBMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL6505142 | 0.81 | ALDH1A1 (0.39) | KMT2AMEN1DCTPP1MAPTSMN1; SMN2 | |
| SCHEMBL6491775 | 0.81 | PPARG (0.54) | MAPTLMNA | |
| SCHEMBL6299335 | 0.81 | PPARG (0.47) | MAPTSMN1; SMN2ALDH1A1NPSR1NPC1 | |
| SCHEMBL6299786 | 0.81 | ALDH1A1 (0.43) | KMT2AMEN1DCTPP1MAPTSMN1; SMN2 | |
| SCHEMBL7839471 | 0.80 | ALDH1A1 (0.42) | KMT2AMEN1DCTPP1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1136492-A1 | SULFONAMIDE COMPOUNDS AND USES THEREOF AS MEDICINES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-09-26 | — | — | EP | disclosed |