SCHEMBL783750

SCHEMBL783750

COC(OC)(OC)OC(C)=O

nearest known ligand 0.44

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.44
GAA P10253 1/20 0.40
TSHR P16473 2/20 0.37
HSD17B10 Q99714 2/20 0.30
LMNA P02545 2/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7896884 0.83 GAA (0.46) ALDH1A1GAATSHRHSD17B10LMNA
SCHEMBL298347 0.73
SCHEMBL784657 0.73 GAA (0.44) ALDH1A1GAATSHR
SCHEMBL19895678 0.73 GAA (0.39) ALDH1A1GAATSHRLMNA
SCHEMBL13003089 0.71 GAA (0.42) ALDH1A1GAATSHR
SCHEMBL784518 0.69 ALDH1A1 (0.36) ALDH1A1GAATSHRHSD17B10TDP1
SCHEMBL783715 0.69 ALDH1A1 (0.43) ALDH1A1GAATSHRHSD17B10LMNA
SCHEMBL783658 0.69 L3MBTL1 (0.32) ALDH1A1TSHR
SCHEMBL784066 0.69 DGAT1 (0.31)
SCHEMBL29212509 0.69 GAA (0.36) ALDH1A1GAATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120070730-A1 NONAQUEOUS ELECTROLYTE AND NONAQUEOUS ELECTROLYTE BATTERY SONY CORPORATION (JP) 2012-03-22 US disclosed
CN-1882557-A 4-oxo-4,5-dihydro-furan-2-carboxylic and acid derivatives and methods of treatment of metabolic-related disorders thereof ARENA PHARM INC (US) 2006-12-20 CN disclosed