Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | LIPE | Q05469 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12265798 | 0.98 | L3MBTL1 (0.49) | L3MBTL1ALDH1A1HTTMAPTGAA | |
| SCHEMBL10266497 | 0.78 | CYP2D6 (0.46) | HTTKDM4ELIPESMN1; SMN2 | |
| SCHEMBL27915480 | 0.78 | GNAI3 (0.45) | L3MBTL1ALDH1A1HTTMAPT | |
| SCHEMBL28514252 | 0.77 | L3MBTL1 (0.47) | L3MBTL1ALDH1A1HTTMAPTGAA | |
| SCHEMBL8861717 | 0.75 | L3MBTL1 (0.43) | L3MBTL1ALDH1A1HTTMAPTGAA | |
| SCHEMBL3557996 | 0.74 | L3MBTL1 (0.44) | L3MBTL1ALDH1A1HTTMAPTGAA | |
| SCHEMBL15054605 | 0.74 | L3MBTL1 (0.45) | L3MBTL1ALDH1A1HTTMAPTGAA | |
| SCHEMBL6123494 | 0.73 | HTT (0.45) | L3MBTL1ALDH1A1HTTMAPTGAA | |
| SCHEMBL637498 | 0.73 | HTT (0.45) | L3MBTL1ALDH1A1HTTMAPTGAA | |
| Hydrochloric Acid SCHEMBL7939486 | 0.73 | L3MBTL1 (0.43) | L3MBTL1ALDH1A1HTTMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8026368-B2 | Hydrazide compounds and thrombopoietin receptor activators | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2011-09-27 | — | — | US | disclosed |
| US-20090253751-A1 | HYDRAZIDE COMPOUND AND THROMBOPOIETIN RECEPTOR ACTIVATOR | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2009-10-08 | — | — | US | disclosed |
| EP-0977740-A4 | METHODS FOR SYNTHESIZING 2-SUBSTITUTED IMIDAZOLES | SEPRACOR INC (US) | 2001-01-17 | — | — | EP | disclosed |
| EP-0977740-A1 | METHODS FOR SYNTHESIZING 2-SUBSTITUTED IMIDAZOLES | SEPRACOR, INC. (US) | 2000-02-09 | — | — | EP | disclosed |
| WO-1998046571-A1 | METHODS FOR SYNTHESIZING 2-SUBSTITUTED IMIDAZOLES | SEPRACOR INC. (US) | 1998-10-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090253751-A1 | HYDRAZIDE COMPOUND AND THROMBOPOIETIN RECEPTOR ACTIVATOR | TEK, THPO, PTAFR | L3MBTL1 2628/4885ALDH1A1 973/4885HTT 160/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.