SCHEMBL78376

SCHEMBL78376

CC(C)(C)c1c[c]cc(-n2nc3ccccc3n2)c1O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 4/20 0.43
RAB9A P51151 4/20 0.43
LMNA P02545 1/20 0.43
POLB P06746 2/20 0.39
CA2 P00918 1/20 0.36
ALDH1A1 P00352 3/20 0.35
KDM4E B2RXH2 3/20 0.35
TDP1 Q9NUW8 2/20 0.35
HPGD P15428 2/20 0.35
TSHR P16473 1/20 0.35
ATM Q13315 1/20 0.35
SMN1; SMN2 Q16637 2/20 0.34
PPARG P37231 1/20 0.33
PPARA Q07869 1/20 0.33
HTT P42858 1/20 0.33
GABRA1 P14867 1/20 0.33
GABRB2 P47870 1/20 0.33
F2R P25116 1/20 0.32
MAPT P10636 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4205932 0.83 NPC1 (0.38) NPC1RAB9ALMNAALDH1A1KDM4E
SCHEMBL29501855 0.81 CA2 (0.52) NPC1RAB9ALMNAPOLBCA2
SCHEMBL424271 0.81 CA2 (0.52) NPC1RAB9ALMNAPOLBCA2
SCHEMBL7869116 0.78 NPC1 (0.50) NPC1RAB9ALMNAPOLBCA2
SCHEMBL29040997 0.78 NPC1 (0.45) NPC1RAB9ALMNAPOLBCA2
SCHEMBL29708 0.77 NPC1 (0.49) NPC1RAB9ALMNAPOLBCA2
SCHEMBL29350736 0.77 NPC1 (0.49) NPC1RAB9ALMNAPOLBCA2
SCHEMBL29365942 0.77 NPC1 (0.64) NPC1RAB9ALMNAPOLBCA2
SCHEMBL208288 0.77 NPC1 (0.64) NPC1RAB9ALMNAPOLBCA2
SCHEMBL9438168 0.75 NPC1 (0.43) NPC1RAB9ALMNAPOLBCA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2578 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9543521-B2 Organic semiconductor device and process for its production BASF SE (DE) 2017-01-10 US claimed
US-20140306212-A1 ORGANIC SEMICONDUCTOR DEVICE AND PROCESS FOR ITS PRODUCTION BASF SE (DE) 2014-10-16 US claimed
EP-2780409-A1 ORGANIC SEMICONDUCTOR DEVICE AND MANUFACTURING METHOD THEREOF BASF SE (DE) 2014-09-24 EP claimed
US-20130306151-A1 ORGANIC PHOTOVOLTAIC DEVICE AND MANUFACTURING METHOD THEREOF BASF SE (DE) 2013-11-21 US claimed
WO-2013072853-A1 ORGANIC SEMICONDUCTOR DEVICE AND MANUFACTURING METHOD THEREOF BASF SE (DE) 2013-05-23 WO claimed
CN-102190954-B Wear-resistant nonskid polyurethane deck paint, and manufacture method thereof TIANJIN BO XING ENGINEERING SCIENCE AND TECHNOLOGY LTD COMPANY OF CNPC 2012-08-15 CN claimed
EP-1814937-B1 ANTIMICROBIAL POLYMER COMPOSITIONS HAVING IMPROVED DISCOLORATION RESISTANCE CIBA HOLDING INC (CH) 2009-07-29 EP claimed
US-20080194731-A1 Antimicrobial Polymer Compositions Having Improved Discoloration Resistance CIBA SPECIALTY CHEMICALS CORP. 2008-08-14 US claimed
EP-1298126-B1 Novel red-shifted triazine ultraviolet light absorbers CYTEC TECH CORP (US) 2008-03-05 EP claimed
US-6916867-B2 Synergistic mixtures of UV-absorbers in polyolefins CIBA SPECIALTY CHEMICALS CORPORATION (US) 2005-07-12 US claimed
US-20030073771-A1 Process for improving the shelf life of a hindered phenol antioxidant CYTEC TECHNOLOGY CORP. 2003-04-17 US claimed
EP-1298126-A1 Novel red-shifted triazine ultraviolet light absorbers CYTEC TECHNOLOGY CORP. (US) 2003-04-02 EP claimed
US-20020161075-A1 Polymeric articles containing hindered amine light stabilizers based on multi-functional carbonyl compounds CYTEC TECHNOLOGY CORP. 2002-10-31 US claimed
WO-2002046136-A2 BIS(ALKYLENEOXYBENZOPHENONE) ULTRAVIOLET LIGHT ABSORBERS CYTEC TECHNOLOGY CORP. (US) 2002-06-13 WO claimed
US-6384113-B1 POLYMER STABILIZER; LOW VOLATILITY; WEATHERABILITY; YELLOWING RESISTANCE CYTEC TECHNOLOGY CORP. 2002-05-07 US claimed
US-20020028937-A1 Benzocycle-substituted triazine and pyrimidine ultraviolet light absorbers CYTEC TECHNOLOGY CORP. 2002-03-07 US claimed
US-6306939-B1 PHOTOSTABILITY, PHOTOGRAPHIC MATERIALS CIBA SPECIALTY CHEMICALS CORPORATION 2001-10-23 US claimed
EP-0665294-B1 Stabilisation of leather against thermic and photochemical decomposition CIBA GEIGY AG (CH) 1999-05-19 EP claimed
US-5705083-A Stabilizing leather against thermal and photochemical decomposition CIBA SPECIALTY CHEMICALS CORPORATION (US) 1998-01-06 US claimed
EP-0665294-A2 Stabilisation of leather against thermic and photochemical decomposition CIBA-GEIGY AG (CH) 1995-08-02 EP claimed