Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.50 |
| ▸ | NPC1 | O15118 | 8/20 | 0.50 |
| ▸ | MEN1 | O00255 | 8/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | TP53 | P04637 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MDM4 | O15151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6777182 | 0.88 | RXFP1 (0.52) | RAB9ANPC1MEN1KMT2ARXFP1 | |
| SCHEMBL3839471 | 0.86 | GPR139 (0.47) | MEN1KMT2AMDM4ITGB3ITGB1 | |
| SCHEMBL7337752 | 0.86 | NPC1 (0.44) | RAB9ANPC1MEN1KMT2AMAPT | |
| SCHEMBL7341726 | 0.84 | GPR139 (0.42) | MEN1KMT2AALDH1A1LMNATSHR | |
| SCHEMBL7838133 | 0.83 | F2 (0.38) | RAB9ANPC1MEN1KMT2AMAPT | |
| SCHEMBL7835632 | 0.83 | ITGB3 (0.49) | RAB9ANPC1MEN1KMT2ARXFP1 | |
| SCHEMBL7340341 | 0.82 | F7 (0.41) | MEN1KMT2ASMN1; SMN2LMNAITGB3 | |
| SCHEMBL7340506 | 0.82 | ITGB3 (0.49) | RAB9ANPC1MEN1KMT2AMAPT | |
| SCHEMBL7338356 | 0.82 | SMN1; SMN2 (0.44) | NPC1MEN1KMT2ASMN1; SMN2TP53 | |
| SCHEMBL7344055 | 0.82 | F7 (0.46) | MAPTSMN1; SMN2ALDH1A1F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0850221-B1 | META-GUANIDINE, UREA, THIOUREA OR AZACYCLIC AMINO BENZOIC ACID DERIVATIVES AS INTEGRIN ANTAGONISTS | SEARLE & CO (US) | 2001-07-18 | — | — | EP | claimed |