Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | MGAM | O43451 | 1/20 | 0.50 |
| ▸ | SI | P14410 | 1/20 | 0.50 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4966366 | 0.89 | MGAM (0.44) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL8574175 | 0.86 | MGAM (0.46) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL1881682 | 0.86 | NAAA (0.38) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL28071761 | 0.84 | KDM4E (0.41) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL21081924 | 0.83 | ALDH1A1 (0.40) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL1879376 | 0.83 | TSHR (0.39) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL10084506 | 0.83 | SOAT1 (0.54) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL16415508 | 0.83 | GAA (0.54) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL1884754 | 0.81 | NAAA (0.47) | ALDH1A1TSHRTDP1L3MBTL1 | |
| SCHEMBL1879615 | 0.81 | ALDH1A1 (0.42) | GAAMGAMSIMGAM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 754 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025111296-A1 | ELECTROLYTE COMPOSITIONS AND ELECTROCHEMICAL DEVICES USING THE SAME | II-VI DELAWARE, INC. (US) | 2025-05-30 | — | — | WO | claimed |
| US-20240376106-A1 | PROCESS OF PREPARING A PD-1/PD-L1 INHIBITOR | INCYTE CORPORATION | 2024-11-14 | — | — | US | claimed |
| US-11780836-B2 | Process of preparing a PD-1/PD-L1 inhibitor | INCYTE CORPORATION (US) | 2023-10-10 | — | — | US | claimed |
| CN-113640431-B | Detection method of strong loquat dew | 江西大自然制药有限公司 | 2023-05-12 | — | — | CN | claimed |
| WO-2022099018-A1 | PROCESS OF PREPARING A PD-1/PD-L1 INHIBITOR | INCYTE CORPORATION (US) | 2022-05-12 | — | — | WO | claimed |
| US-20220144830-A1 | PROCESS OF PREPARING A PD-1/PD-L1 INHIBITOR | INCYTE CORPORATION | 2022-05-12 | — | — | US | claimed |
| CN-114436809-A | Method for preparing diethyl maleate by carrying out depolymerization on lignin under catalysis of iron oxide loaded by USY molecular sieve | 华南理工大学 | 2022-05-06 | — | — | CN | claimed |
| CN-113640431-A | Detection method of strong loquat syrup | 江西大自然制药有限公司 | 2021-11-12 | — | — | CN | claimed |
| CN-108484497-B | Synthetic method of 3-amino-7-chloroquinoline | 苏州康润医药有限公司 | 2021-05-04 | — | — | CN | claimed |
| CN-111825670-A | Tetrahydrocarboline derivative, preparation method thereof and application thereof in preparing antihypertensive drug | 复旦大学 | 2020-10-27 | — | — | CN | claimed |
| CN-104230880-B | The simple and convenient process for preparing of 2-((4R, 6R)-6-aminoethyl-2,2-dimethyl-1,3-dioxane-4-yl) acetic acid esters | XINFA PHARMACEUTICAL CO., LTD. (CN) | 2016-05-04 | — | — | CN | claimed |
| CN-104230880-A | Simple preparation method of 2-((4R,6R)-6-aminoethyl-2,2-dimethyl-1,3-dioxyhexacyclo-4-yl)acetate | XINFA PHARMACEUTICAL CO LTD | 2014-12-24 | — | — | CN | claimed |
| CN-104230990-A | 2-((4R,6S)-6-triphenylphosphoalkenylmethylene-2,2-disubstituted-1,3-dioxyhexacyclo-4-yl)acetate, and preparation method and application thereof | XINFA PHARMACEUTICAL CO LTD | 2014-12-24 | — | — | CN | claimed |
| US-7034154-B2 | Synthesis of substituted pyrazolopyrimidines | NEUROCRINE BIOSCIENCES, INC. (US) | 2006-04-25 | — | — | US | claimed |
| JP-2003506453-A | — | — | 2003-02-18 | — | — | JP | claimed |
| US-20030004346-A1 | Synthesis of substituted pyrazolopyrimidines | NEUROCRINE BIOSCIENCES, INC. (US) | 2003-01-02 | — | — | US | claimed |
| US-6472528-B1 | TREATING CONDITIONS WHICH BENEFIT FROM ADMINISTRATION OF AGENTS WHICH POSSESS ANXIOLYTIC, ANTI-ANOXIC, SLEEP-INDUCING, HYPNOTIC, ANTICONVULSANT, AND/OR SKELETAL MUSCLE RELAXANT PROPERTIES. SUCH CONDITIONS INCLUDE INSOMNIA | NEUROCRINE BIOSCIENCES, INC. | 2002-10-29 | — | — | US | claimed |
| CN-1372561-A | Synthesis of Substituted Pyrazolopyrimidines | NEUROCRINE BIOSCIENCES INC (US) | 2002-10-02 | — | — | CN | claimed |
| EP-1208102-A1 | SYNTHESIS OF SUBSTITUTED PYRAZOLOPYRIMIDINES | Neurocrine Biosciences, Inc. (US) | 2002-05-29 | — | — | EP | claimed |
| WO-2001010868-A1 | SYNTHESIS OF SUBSTITUTED PYRAZOLOPYRIMIDINES | NEUROCRINE BIOSCIENCES, INC. (US) | 2001-02-15 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030004346-A1 | Synthesis of substituted pyrazolopyrimidines | INMT, TPMT, HNMT | GAA 3432/4885MGAM 2561/4885SI 1937/4885 |
| US-11780836-B2 | Process of preparing a PD-1/PD-L1 inhibitor | PDCD1, CD274, PDCD1LG2 | GAA 1241/4885MGAM 2111/4885SI 1310/4885 |
| US-20240376106-A1 | PROCESS OF PREPARING A PD-1/PD-L1 INHIBITOR | PDCD1, CD274, PDCD1LG2 | GAA 1241/4885MGAM 2111/4885SI 1310/4885 |
| US-20220144830-A1 | PROCESS OF PREPARING A PD-1/PD-L1 INHIBITOR | PDCD1, CD274, PDCD1LG2 | GAA 1241/4885MGAM 2111/4885SI 1310/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.