Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN4A | P35499 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7836938 | 0.86 | L3MBTL1 (0.41) | LMNASMN1; SMN2HPGDMEN1KMT2A | |
| SCHEMBL3140336 | 0.83 | KDM4E (0.47) | CYP1A2HIF1ALMNASMN1; SMN2HPGD | |
| SCHEMBL7837854 | 0.81 | ALDH1A1 (0.58) | SCN4AALDH1A1TDP1NPC1 | |
| SCHEMBL7828716 | 0.81 | ALDH1A1 (0.58) | SCN4AALDH1A1TDP1NPC1 | |
| SCHEMBL3135510 | 0.79 | GRM2 (0.50) | NPC1 | |
| SCHEMBL7828558 | 0.78 | ALDH1A1 (0.43) | CYP2C9LMNAHPGDALDH1A1TSHR | |
| SCHEMBL7842308 | 0.77 | TAAR1 (0.57) | HIF1ALMNASMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL7836967 | 0.77 | GRM2 (0.54) | LMNASMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL7842079 | 0.76 | ALDH1A1 (0.44) | SMN1; SMN2MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL11883000 | 0.75 | TAAR1 (0.32) | TSHRTAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0710658-B1 | 5-(Aryloxymethyl)oxazolines, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2001-10-04 | — | — | EP | disclosed |
| EP-0710658-A1 | 5-(Aryloxymethyl)oxazolines, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1996-05-08 | — | — | EP | disclosed |