Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.38 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7836938 | 0.89 | L3MBTL1 (0.41) | ALDH1A1HPGDTSHRGLAMAPT | |
| SCHEMBL7828716 | 0.83 | ALDH1A1 (0.58) | ALDH1A1GLAMAPTTDP1KDM4E | |
| SCHEMBL7837854 | 0.83 | ALDH1A1 (0.58) | ALDH1A1GLAMAPTTDP1KDM4E | |
| SCHEMBL7840000 | 0.80 | GRM2 (0.55) | ALDH1A1TSHRTDP1POLB | |
| SCHEMBL3144469 | 0.79 | RAB9A (0.42) | ALDH1A1TSHRNPC1RAB9A | |
| SCHEMBL7838599 | 0.78 | SCN4A (0.41) | ALDH1A1HPGDTSHRTDP1GAA | |
| SCHEMBL7842079 | 0.78 | ALDH1A1 (0.44) | ALDH1A1TSHRGLAMAPTGAA | |
| SCHEMBL3140336 | 0.77 | KDM4E (0.47) | ALDH1A1HPGDTSHRGLAMAPT | |
| SCHEMBL7829999 | 0.76 | ADRA2C (0.49) | ALDH1A1GLAMAPTKDM4ENPC1 | |
| SCHEMBL7840162 | 0.76 | HTR2A (0.49) | ALDH1A1GLAMAPTALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0710658-B1 | 5-(Aryloxymethyl)oxazolines, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2001-10-04 | — | — | EP | claimed |
| US-5686477-A | HYPOTENSIVE AGENTS | ADIR ET COMPAGNIE (FR) | 1997-11-11 | — | — | US | claimed |
| EP-0710658-A1 | 5-(Aryloxymethyl)oxazolines, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1996-05-08 | — | — | EP | claimed |
| EP-0710658-B1 | 5-(Aryloxymethyl)oxazolines, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2001-10-04 | — | — | EP | disclosed |
| EP-0710658-A1 | 5-(Aryloxymethyl)oxazolines, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1996-05-08 | — | — | EP | disclosed |