Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.52 |
| ▸ | ACACB | O00763 | 11/20 | 0.52 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.48 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.47 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | YAP1 | P46937 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7847062 | 0.97 | ACACB (0.48) | HRH3ACACBSLC2A1GPR119YAP1 | |
| SCHEMBL7847387 | 0.89 | GPR119 (0.52) | HRH3ACACBGPR119YAP1 | |
| SCHEMBL7838252 | 0.82 | GPR119 (0.50) | HRH3ACACBGPR119KDM1A | |
| SCHEMBL7849387 | 0.81 | GPR119 (0.55) | HRH3ACACBGPR119YAP1 | |
| SCHEMBL7847033 | 0.81 | GPR119 (0.61) | ACACBGPR119YAP1 | |
| SCHEMBL7848490 | 0.81 | GPR119 (0.47) | GPR119KDM1A | |
| SCHEMBL7847345 | 0.80 | ACHE (0.43) | GPR119KDM1A | |
| SCHEMBL6190651 | 0.79 | F10 (0.56) | HRH3SLC2A1TMEM97SIGMAR1YAP1 | |
| SCHEMBL7847275 | 0.79 | ACHE (0.42) | GPR119KDM1A | |
| Hydrochloric Acid SCHEMBL7848692 | 0.79 | HRH3 (0.60) | HRH3ACACBTMEM97SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1122252-A1 | NITROGENOUS FUSED HETEROCYCLE COMPOUNDS, PROCESS FOR THE PREPARATION THEREOF AND AGENTS CONTAINING THE SAME | Takeda Chemical Industries, Ltd. (JP) | 2001-08-08 | — | — | EP | disclosed |