Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 12/20 | 0.47 |
| ▸ | STS | P08842 | 1/20 | 0.44 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.42 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7855571 | 0.90 | GPR119 (0.52) | GPR119STSTGFBR1KDM4EPKM | |
| SCHEMBL7850501 | 0.86 | ACHE (0.51) | ACHE | |
| SCHEMBL7847387 | 0.85 | GPR119 (0.52) | GPR119 | |
| SCHEMBL7847062 | 0.84 | ACACB (0.48) | GPR119 | |
| SCHEMBL7847275 | 0.84 | ACHE (0.42) | GPR119STSACHEKDM1ANPC1 | |
| SCHEMBL7847345 | 0.83 | ACHE (0.43) | GPR119STSACHEKDM1ANPC1 | |
| SCHEMBL7848598 | 0.82 | GPR119 (0.49) | GPR119NPC1RAB9APKM | |
| SCHEMBL7838652 | 0.81 | HRH3 (0.52) | GPR119KDM1A | |
| SCHEMBL7847148 | 0.79 | GPR119 (0.51) | GPR119NPC1RAB9A | |
| SCHEMBL7847185 | 0.79 | GPR119 (0.54) | GPR119NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1122252-A1 | NITROGENOUS FUSED HETEROCYCLE COMPOUNDS, PROCESS FOR THE PREPARATION THEREOF AND AGENTS CONTAINING THE SAME | Takeda Chemical Industries, Ltd. (JP) | 2001-08-08 | — | — | EP | disclosed |