Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 6/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.54 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | UBE2N | P61088 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17113293 | 0.81 | NR4A2 (0.70) | NR4A2ALDH1A1LMNAMAPTHTT | |
| SCHEMBL2036909 | 0.79 | NR4A2 (1.00) | NR4A2ALDH1A1LMNAMAPTHTT | |
| SCHEMBL9936554 | 0.78 | NR4A2 (0.70) | NR4A2ALDH1A1LMNAMAPTHTT | |
| SCHEMBL2034149 | 0.78 | NR4A2 (0.70) | NR4A2ALDH1A1LMNAMAPTHTT | |
| SCHEMBL2040417 | 0.78 | NR4A2 (1.00) | NR4A2ALDH1A1LMNAMAPTHTT | |
| SCHEMBL9936453 | 0.74 | NR4A2 (0.65) | NR4A2ALDH1A1LMNAMAPTHTT | |
| SCHEMBL2035481 | 0.74 | NR4A2 (0.65) | NR4A2ALDH1A1LMNAMAPTHTT | |
| SCHEMBL26185203 | 0.74 | NR4A2 (0.41) | NR4A2ALDH1A1LMNAMAPTHTT | |
| SCHEMBL7004599 | 0.73 | ALDH1A1 (0.62) | NR4A2ALDH1A1LMNAMAPTHTT | |
| SCHEMBL30945155 | 0.73 | ALDH1A1 (0.67) | ALDH1A1LMNAMAPTHTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140946-A2 | QUINOLINE DERIVATIVES | SMITHKLINE BEECHAM PLC (GB) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000035919-A2 | QUINOLINE DERIVATIVES | SMITHKLINE BEECHAM PLC (GB) | 2000-06-22 | — | — | WO | disclosed |