Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 5/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5510284 | 0.93 | PTGS2 (0.51) | PTGDR2PTGS2GAAL3MBTL1MEN1 | |
| SCHEMBL5516266 | 0.93 | PTGS2 (0.51) | PTGDR2PTGS2GAAL3MBTL1MEN1 | |
| SCHEMBL792073 | 0.79 | PTGS2 (0.52) | PTGDR2PTGS2GAAMEN1KMT2A | |
| SCHEMBL7839943 | 0.78 | TRPM8 (0.55) | PTGS2MEN1KMT2A | |
| SCHEMBL11150568 | 0.77 | PTGDR2 (0.43) | PTGDR2 | |
| SCHEMBL791811 | 0.75 | PTGS2 (0.49) | PTGDR2PTGS2GAAMEN1KMT2A | |
| SCHEMBL8188473 | 0.71 | ALDH1A1 (0.61) | PTGS2 | |
| SCHEMBL29764150 | 0.68 | PTGS2 (0.51) | PTGS2 | |
| SCHEMBL1340065 | 0.68 | TRPM8 (0.62) | PTGS2MEN1KMT2A | |
| SCHEMBL6598899 | 0.67 | PTGDR2 (0.43) | PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1162196-A1 | FUSED-RING COMPOUNDS AND USE THEREOF AS DRUGS | JAPAN TOBACCO INC. (JP) | 2001-12-12 | — | — | EP | disclosed |