Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 11/20 | 0.50 |
| ▸ | EDNRB | P24530 | 10/20 | 0.50 |
| ▸ | DHPS | P49366 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7839629 | 1.00 | EDNRA (0.50) | EDNRAEDNRBDHPSALDH1A1HTT | |
| SCHEMBL7844686 | 0.94 | DHPS (0.54) | EDNRAEDNRBDHPSALDH1A1HTT | |
| SCHEMBL7844683 | 0.94 | DHPS (0.54) | EDNRAEDNRBDHPSALDH1A1HTT | |
| SCHEMBL7843519 | 0.90 | ALDH1A1 (0.46) | EDNRAEDNRBDHPSALDH1A1HTT | |
| SCHEMBL7843522 | 0.90 | ALDH1A1 (0.46) | EDNRAEDNRBDHPSALDH1A1HTT | |
| SCHEMBL7844692 | 0.90 | EDNRA (0.62) | EDNRAEDNRBALDH1A1HTT | |
| SCHEMBL7844690 | 0.90 | EDNRA (0.62) | EDNRAEDNRBALDH1A1HTT | |
| SCHEMBL7842387 | 0.89 | DHPS (0.47) | EDNRAEDNRBDHPSALDH1A1HTT | |
| SCHEMBL7842383 | 0.89 | DHPS (0.47) | EDNRAEDNRBDHPSALDH1A1HTT | |
| SCHEMBL7840232 | 0.89 | ALDH1A1 (0.47) | EDNRAEDNRBDHPSALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882719-B1 | ARYLETHENESULFONAMIDE DERIVATIVES AND DRUG COMPOSITION CONTAINING THE SAME | YAMANOUCHI PHARMA CO LTD (JP) | 2001-05-16 | — | — | EP | disclosed |
| US-6083955-A | HAVING A HIGH AFFINITY FOR DRUGS, ESPECIALLY ENDOSERINE RECEPTORS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 2000-07-04 | — | — | US | disclosed |
| EP-0882719-A1 | ARYLETHENESULFONAMIDE DERIVATIVES AND DRUG COMPOSITION CONTAINING THE SAME | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1998-12-09 | — | — | EP | disclosed |