Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | DHPS | P49366 | 5/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | EDNRA | P25101 | 5/20 | 0.44 |
| ▸ | EDNRB | P24530 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7843522 | 1.00 | ALDH1A1 (0.46) | ALDH1A1KMT2AMAPTGAAMEN1 | |
| SCHEMBL7844686 | 0.92 | DHPS (0.54) | ALDH1A1DHPSHTTEDNRAEDNRB | |
| SCHEMBL7844683 | 0.92 | DHPS (0.54) | ALDH1A1DHPSHTTEDNRAEDNRB | |
| SCHEMBL7830607 | 0.90 | EDNRA (0.55) | ALDH1A1KMT2AMAPTGAAMEN1 | |
| SCHEMBL7830604 | 0.90 | EDNRA (0.55) | ALDH1A1KMT2AMAPTGAAMEN1 | |
| SCHEMBL7839629 | 0.90 | EDNRA (0.50) | ALDH1A1DHPSHTTEDNRAEDNRB | |
| SCHEMBL7839633 | 0.90 | EDNRA (0.50) | ALDH1A1DHPSHTTEDNRAEDNRB | |
| SCHEMBL7840413 | 0.88 | ALDH1A1 (0.45) | ALDH1A1DHPSHTTEDNRAEDNRB | |
| SCHEMBL7840415 | 0.88 | ALDH1A1 (0.45) | ALDH1A1DHPSHTTEDNRAEDNRB | |
| SCHEMBL7840232 | 0.86 | ALDH1A1 (0.47) | ALDH1A1DHPSHTTEDNRAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882719-B1 | ARYLETHENESULFONAMIDE DERIVATIVES AND DRUG COMPOSITION CONTAINING THE SAME | YAMANOUCHI PHARMA CO LTD (JP) | 2001-05-16 | — | — | EP | disclosed |
| US-6083955-A | HAVING A HIGH AFFINITY FOR DRUGS, ESPECIALLY ENDOSERINE RECEPTORS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 2000-07-04 | — | — | US | disclosed |
| EP-0882719-A1 | ARYLETHENESULFONAMIDE DERIVATIVES AND DRUG COMPOSITION CONTAINING THE SAME | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1998-12-09 | — | — | EP | disclosed |