Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 11/20 | 0.40 |
| ▸ | CTRB1 | P17538 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.34 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7845411 | 0.93 | ELANE (0.46) | ELANECTRB1 | |
| SCHEMBL6498899 | 0.88 | ELANE (0.38) | ELANECTRB1POLBMAPTKMT2A | |
| SCHEMBL7829580 | 0.84 | ELANE (0.43) | ELANECTRB1KMT2A | |
| SCHEMBL6500724 | 0.83 | ELANE (0.43) | ELANECTRB1 | |
| SCHEMBL6500847 | 0.82 | ELANE (0.45) | ELANECTRB1 | |
| SCHEMBL6805471 | 0.81 | ELANE (0.43) | ELANECTRB1 | |
| SCHEMBL6503610 | 0.81 | CTRB1 (0.49) | ELANECTRB1POLBKMT2A | |
| SCHEMBL7840487 | 0.79 | CTRB1 (0.53) | ELANECTRB1KMT2A | |
| SCHEMBL27382349 | 0.79 | ELANE (0.59) | ELANECTRB1 | |
| SCHEMBL7447429 | 0.78 | ELANE (0.47) | ELANECTRB1MAPTKMT2AITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828721-B1 | 2-AMINO-BENZOXAZINONES FOR THE TREATMENT OF VIRAL INFECTIONS | SEARLE & CO (US) | 2001-11-14 | — | — | EP | claimed |