Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRB1 | P17538 | 6/20 | 0.53 |
| ▸ | ELANE | P08246 | 14/20 | 0.47 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7839987 | 0.91 | CTRB1 (0.46) | CTRB1ELANEKMT2AMMP1 | |
| SCHEMBL7844510 | 0.88 | CTRB1 (0.45) | CTRB1ELANEGPR139ALDH1A1KMT2A | |
| SCHEMBL7813812 | 0.84 | CTRB1 (0.52) | CTRB1ELANEGPR139ALDH1A1KMT2A | |
| SCHEMBL7845411 | 0.84 | ELANE (0.46) | CTRB1ELANEALDH1A1 | |
| SCHEMBL6498129 | 0.83 | ELANE (0.44) | CTRB1ELANE | |
| SCHEMBL7829580 | 0.82 | ELANE (0.43) | CTRB1ELANEALDH1A1KMT2A | |
| SCHEMBL6500847 | 0.82 | ELANE (0.45) | CTRB1ELANE | |
| SCHEMBL7840950 | 0.81 | CTRB1 (0.43) | CTRB1ELANEKMT2A | |
| SCHEMBL7831962 | 0.80 | CTRB1 (0.42) | CTRB1ELANEALDH1A1KMT2A | |
| SCHEMBL7840282 | 0.79 | ELANE (0.40) | CTRB1ELANEKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828721-B1 | 2-AMINO-BENZOXAZINONES FOR THE TREATMENT OF VIRAL INFECTIONS | SEARLE & CO (US) | 2001-11-14 | — | — | EP | disclosed |