Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PGK1 | P00558 | 1/20 | 0.33 |
| ▸ | PGK2 | P07205 | 1/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | AHR | P35869 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CASP6 | P55212 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10595586 | 0.83 | LMNA (0.54) | LMNAKCNH2ALDH1A1MEN1KMT2A | |
| SCHEMBL4961500 | 0.79 | LMNA (0.47) | LMNAKCNH2MEN1KMT2AMAPT | |
| SCHEMBL4379609 | 0.78 | MRGPRX4 (0.54) | LMNAKMT2AMRGPRX4TDP1KDM4E | |
| SCHEMBL14394483 | 0.75 | LMNA (0.47) | LMNAKCNH2 | |
| SCHEMBL18107068 | 0.73 | LMNA (0.45) | LMNAKCNH2PGK1PGK2 | |
| SCHEMBL10595532 | 0.72 | LMNA (0.44) | LMNAALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL4532460 | 0.72 | LMNA (0.44) | LMNAKCNH2ALDH1A1MAPTMRGPRX4 | |
| SCHEMBL19212962 | 0.71 | KMT2A (0.49) | LMNAKCNH2ALDH1A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL10596067 | 0.71 | LMNA (0.43) | LMNAALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL7828216 | 0.69 | PTGS2 (0.44) | LMNAALDH1A1KMT2ATDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1154999-A1 | NITROXYDERIVATIVES HAVING ANTIINFLAMMATORY, ANALGESIC AND ANTITHROMBOTIC ACTIVITY | NICOX S.A. (FR) | 2001-11-21 | — | — | EP | disclosed |
| WO-2000051988-A1 | NITROXYDERIVATIVES HAVING ANTIINFLAMMATORY, ANALGESIC AND ANTITHROMBOTIC ACTIVITY | NICOX S.A. (FR) | 2000-09-08 | — | — | WO | disclosed |