Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | KDM1A | O60341 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | CKS1B | P61024 | 3/20 | 0.42 |
| ▸ | SKP2 | Q13309 | 3/20 | 0.42 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7014524 | 0.84 | RAB9A (0.47) | RAB9ANPC1SMN1; SMN2KDM1AHSD17B10 | |
| SCHEMBL8825734 | 0.82 | HSD17B10 (0.45) | RAB9ANPC1SMN1; SMN2KDM1AHSD17B10 | |
| SCHEMBL7840913 | 0.82 | RAB9A (0.48) | RAB9ANPC1SMN1; SMN2KDM1AHSD17B10 | |
| SCHEMBL7017512 | 0.79 | ALDH1A1 (0.46) | RAB9ANPC1SMN1; SMN2KDM1AHSD17B10 | |
| SCHEMBL8825655 | 0.78 | HSD17B10 (0.47) | RAB9ANPC1SMN1; SMN2KDM1AHSD17B10 | |
| SCHEMBL8825669 | 0.76 | HSD17B10 (0.45) | RAB9ANPC1SMN1; SMN2KDM1AHSD17B10 | |
| SCHEMBL8825674 | 0.76 | NPC1 (0.46) | RAB9ANPC1SMN1; SMN2KDM1AHSD17B10 | |
| SCHEMBL7013765 | 0.75 | RAB9A (0.57) | RAB9ANPC1SMN1; SMN2KDM1AHSD17B10 | |
| SCHEMBL7019011 | 0.73 | CKS1B (0.45) | RAB9ANPC1SMN1; SMN2KDM1AHSD17B10 | |
| SCHEMBL7851305 | 0.73 | ALDH1A1 (0.57) | RAB9ANPC1SMN1; SMN2KDM1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0717743-B1 | N-ARYL 1,2,4]TRIAZOLO 1,5-a]PYRIDINE-2-SULFONAMIDE HERBICIDES | DOW AGROSCIENCES LLC (US) | 2001-11-14 | — | — | EP | disclosed |
| EP-0972774-A2 | 2-Benzylthio-8-amino(1,2,4)triazolo(1,5-pyridines | Dow AgroSciences LLC (US) | 2000-01-19 | — | — | EP | disclosed |
| US-5571775-A | EFFECTIVE ON A BROAD SPECTRUM OF VEGETATION AT LOW APPLICATION RATES | DOWELANCO (US) | 1996-11-05 | — | — | US | disclosed |
| WO-1996001826-A1 | N-ARYL[1,2,4]TRIAZOLO[1,5-a]PYRIDINE-2-SULFONAMIDE HERBICIDES | DOWELANCO (US) | 1996-01-25 | — | — | WO | disclosed |