Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 6/20 | 0.33 |
| ▸ | TOP2B | Q02880 | 6/20 | 0.33 |
| ▸ | DPP4 | P27487 | 5/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.33 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.33 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7850907 | 0.90 | ALDH1A1 (0.35) | DPP4POLBALDH1A1OPRM1CHRM2 | |
| Bromide SCHEMBL7841713 | 0.89 | ALDH1A1 (0.35) | DPP4POLBALDH1A1OPRM1CHRM2 | |
| Hydrochloric Acid SCHEMBL7848827 | 0.89 | ALDH1A1 (0.35) | DPP4POLBALDH1A1OPRM1CHRM2 | |
| SCHEMBL7841767 | 0.89 | TOP2A (0.44) | TOP2ATOP2BDPP4KCNH2POLB | |
| SCHEMBL7853924 | 0.86 | TOP2A (0.32) | TOP2ATOP2BDPP4POLBALDH1A1 | |
| SCHEMBL9416438 | 0.85 | KCNH2 (0.38) | TOP2ATOP2BDPP4KCNH2POLB | |
| SCHEMBL8133386 | 0.85 | ALDH1A1 (0.43) | TOP2ATOP2BKCNH2POLBCACNA1F | |
| Hydrochloric Acid SCHEMBL9416466 | 0.84 | KCNH2 (0.38) | TOP2ATOP2BDPP4KCNH2POLB | |
| SCHEMBL7841772 | 0.83 | EPHA2 (0.45) | DPP4POLBKMT2AALDH1A1KDM4E | |
| SCHEMBL7851048 | 0.82 | PIK3CG (0.33) | TOP2ATOP2BDPP4ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0726270-B1 | Derivatives of 1,6-naphthyridone carboxylic acids | BAYER AG (DE) | 2001-05-23 | — | — | EP | disclosed |
| EP-0726270-A1 | Derivatives of 1,6-naphthyridine carboxylic acids | BAYER AG (DE) | 1996-08-14 | — | — | EP | disclosed |