Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 2/20 | 0.42 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7200824 | 0.84 | GRIK1 (0.50) | GRIK1GRIK2CA1CA2 | |
| SCHEMBL26616598 | 0.83 | GRIK1 (0.47) | GRIK1GRIK2CA1CA2 | |
| SCHEMBL17822475 | 0.81 | CA1 (0.45) | GRIK1GRIK2CA1CA2 | |
| SCHEMBL474901 | 0.78 | CA2 (0.42) | CA1CA2 | |
| SCHEMBL2479818 | 0.78 | CA2 (0.62) | GRIK1GRIK2CA1CA2 | |
| SCHEMBL805202 | 0.76 | — | — | |
| SCHEMBL1685420 | 0.74 | — | — | |
| SCHEMBL1230306 | 0.70 | CA1 (0.37) | CA1CA2 | |
| SCHEMBL4255669 | 0.70 | — | — | |
| SCHEMBL8306591 | 0.70 | CA1 (0.37) | CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1105376-A1 | OXINDOLE DERIVATIVES AS GROWTH HORMONE RELEASERS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2001-06-13 | — | — | EP | disclosed |
| WO-2000010975-A1 | OXINDOLE DERIVATIVES AS GROWTH HORMONE RELEASERS | SUMITOMO PHARMACEUTICALS CO., LTD. (JP) | 2000-03-02 | — | — | WO | disclosed |