Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GCK | P35557 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | EPAS1 | Q99814 | 4/20 | 0.36 |
| ▸ | CCR2 | P41597 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL282188 | 0.82 | L3MBTL1 (0.62) | L3MBTL1MEN1KMT2ACYP3A4TSHR | |
| SCHEMBL30431062 | 0.82 | L3MBTL1 (0.62) | L3MBTL1MEN1KMT2ACYP3A4TSHR | |
| SCHEMBL7841878 | 0.74 | GRM4 (0.40) | GCKCYP3A4ALDH1A1EPAS1CCR2 | |
| SCHEMBL1581780 | 0.71 | HSD11B1 (0.48) | L3MBTL1MEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL29430629 | 0.71 | HSD11B1 (0.48) | L3MBTL1MEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL116722 | 0.71 | — | — | |
| SCHEMBL10184964 | 0.69 | L3MBTL1 (0.59) | L3MBTL1MEN1KMT2ACYP3A4TSHR | |
| SCHEMBL31623389 | 0.69 | L3MBTL1 (0.59) | L3MBTL1MEN1KMT2ACYP3A4TSHR | |
| Bromide SCHEMBL1454620 | 0.69 | KMT2A (0.41) | MEN1KMT2AALDH1A1ALOX15 | |
| SCHEMBL12496190 | 0.68 | L3MBTL1 (0.62) | L3MBTL1MEN1KMT2ACYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1137647-A1 | THIOUREA INHIBITORS OF HERPES VIRUSES | AMERICAN HOME PRODUCTS CORPORATION (US) | 2001-10-04 | — | — | EP | disclosed |
| WO-2000034268-A1 | THIOUREA INHIBITORS OF HERPES VIRUSES | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-06-15 | — | — | WO | disclosed |