Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 5/20 | 0.39 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.39 |
| ▸ | GCK | P35557 | 2/20 | 0.37 |
| ▸ | CCR2 | P41597 | 1/20 | 0.36 |
| ▸ | EPAS1 | Q99814 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7841874 | 0.74 | L3MBTL1 (0.44) | GRM4PPARGGCKCCR2EPAS1 | |
| SCHEMBL12276475 | 0.72 | CA1 (0.55) | PPARGSLC22A12ALDH1A1CYP3A4CA1 | |
| SCHEMBL1581780 | 0.70 | HSD11B1 (0.48) | GRM4CCR2ALDH1A1CA1CA2 | |
| SCHEMBL29430629 | 0.70 | HSD11B1 (0.48) | GRM4CCR2ALDH1A1CA1CA2 | |
| SCHEMBL6534946 | 0.70 | GRM4 (0.46) | GRM4PPARGCCR2NPC1ALDH1A1 | |
| SCHEMBL22447441 | 0.69 | SLC22A12 (0.55) | PPARGSLC22A12CYP3A4CA1CA2 | |
| Hydrochloric Acid SCHEMBL6512600 | 0.68 | GRM4 (0.45) | GRM4PPARGCCR2NPC1ALDH1A1 | |
| SCHEMBL856308 | 0.68 | PIK3CB (0.54) | SLC22A12 | |
| SCHEMBL2312129 | 0.66 | ALDH1A1 (0.69) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL12186139 | 0.65 | L3MBTL1 (0.44) | GRM4CCR2ALDH1A1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1137647-A1 | THIOUREA INHIBITORS OF HERPES VIRUSES | AMERICAN HOME PRODUCTS CORPORATION (US) | 2001-10-04 | — | — | EP | disclosed |
| WO-2000034268-A1 | THIOUREA INHIBITORS OF HERPES VIRUSES | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-06-15 | — | — | WO | disclosed |