Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | KIF11 | P52732 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.37 |
| ▸ | ERN1 | O75460 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5406345 | 0.78 | ALDH1A1 (0.50) | ALDH1A1CYP2A6CYP1A2KIF11NPC1 | |
| SCHEMBL29951294 | 0.78 | CYP1A2 (0.57) | ALDH1A1CYP2A6CYP1A2KIF11NPC1 | |
| SCHEMBL2996328 | 0.78 | ERN1 (0.45) | ALDH1A1CYP2A6CYP1A2KIF11NPC1 | |
| SCHEMBL31141573 | 0.78 | ERN1 (0.45) | ALDH1A1CYP2A6CYP1A2KIF11NPC1 | |
| SCHEMBL6362144 | 0.78 | CYP1A2 (0.57) | ALDH1A1CYP2A6CYP1A2KIF11NPC1 | |
| SCHEMBL1775016 | 0.76 | ALDH1A1 (0.41) | ALDH1A1CYP2A6CYP1A2KIF11CA1 | |
| SCHEMBL29952947 | 0.76 | HPRT1 (0.42) | ALDH1A1CYP2A6CYP1A2KIF11CA1 | |
| SCHEMBL6200530 | 0.76 | NQO2 (0.55) | ALDH1A1CYP2A6CYP1A2RAB9AHSD17B10 | |
| SCHEMBL28139963 | 0.76 | CYP2A6 (0.39) | ALDH1A1CYP2A6CYP1A2KIF11CA1 | |
| SCHEMBL9100053 | 0.76 | ALDH1A1 (0.45) | ALDH1A1CYP2A6CYP1A2KIF11NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0454501-B1 | Benzylidenethiazolidine derivatives, their preparation and their use for the inhibition of lipid peroxides | SANKYO CO (JP) | 2001-09-05 | — | — | EP | disclosed |
| EP-0839812-A1 | Preparation of benzylthiazolidine derivatives | Sankyo Company Limited (JP) | 1998-05-06 | — | — | EP | disclosed |
| US-5387596-A | Treating arteriosclerosis | SANKYO COMPANY, LIMITED (JP) | 1995-02-07 | — | — | US | disclosed |
| EP-0254578-B1 | ANTIBIOTIC INTERMEDIATES | ELI LILLY AND COMPANY (US) | 1993-09-08 | — | — | EP | disclosed |
| EP-0454501-A2 | Benzylidenethiazolidine derivatives, their preparation and their use for the inhibition of lipid peroxides | Sankyo Company Limited (JP) | 1991-10-30 | — | — | EP | disclosed |
| US-4772694-A | Chiral 3-(1,2,5-trisubstituted imidazolidinone) azetidinone antibiotic intermediates | ELI LILLY AND COMPANY (US) | 1988-09-20 | — | — | US | disclosed |
| EP-0254578-A1 | Antibiotic intermediates | ELI LILLY AND COMPANY (US) | 1988-01-27 | — | — | EP | disclosed |