Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.40 |
| ▸ | HTR1E | P28566 | 1/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | NHERF1 | O14745 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28030677 | 0.70 | KMT2A (0.61) | KMT2AHSD17B10GAAALDH1A1CYP3A4 | |
| SCHEMBL16620979 | 0.70 | KMT2A (0.61) | KMT2AHSD17B10RORCMEN1POLB | |
| SCHEMBL21020739 | 0.70 | MAPT (0.48) | KMT2AHSD17B10RORCMEN1ALDH1A1 | |
| SCHEMBL4273466 | 0.70 | SRC (0.66) | HSD17B10ALDH1A1CYP3A4TDP1NPBWR1 | |
| SCHEMBL27652680 | 0.70 | HSD17B10 (0.58) | KMT2AHSD17B10RORCMEN1POLB | |
| SCHEMBL1789120 | 0.70 | KMT2A (0.75) | KMT2AHSD17B10RORCMEN1ALDH1A1 | |
| Methylamine SCHEMBL11821451 | 0.69 | ALDH1A1 (0.62) | KMT2AHSD17B10MEN1ALDH1A1CYP3A4 | |
| SCHEMBL29739558 | 0.69 | ALDH1A1 (0.67) | KMT2AHSD17B10RORCMEN1ALDH1A1 | |
| SCHEMBL431298 | 0.69 | ALDH1A1 (0.67) | KMT2AHSD17B10RORCMEN1ALDH1A1 | |
| SCHEMBL305393 | 0.69 | ALDH1A1 (0.67) | KMT2AHSD17B10RORCMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1150565-A1 | THIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | LION bioscience AG (DE) | 2001-11-07 | — | — | EP | disclosed |
| WO-2000045635-A1 | THIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | LION BIOSCIENCE AG (DE) | 2000-08-10 | — | — | WO | disclosed |