Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.61 |
| ▸ | RORC | P51449 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | THPO | P40225 | 1/20 | 0.49 |
| ▸ | MTOR | P42345 | 1/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8914718 | 0.82 | PTPRC (0.51) | KMT2AMEN1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL10752700 | 0.81 | ALDH1A1 (0.51) | KMT2AMEN1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL1789120 | 0.80 | KMT2A (0.75) | KMT2ARORCMEN1CYP1A2CYP3A4 | |
| SCHEMBL4238940 | 0.79 | KDM4E (0.52) | KMT2AMEN1SMN1; SMN2TP53MAPT | |
| Dinitrophenylene SCHEMBL27563939 | 0.78 | KMT2A (0.67) | KMT2ARORCMEN1CYP1A2CYP3A4 | |
| SCHEMBL27958260 | 0.78 | KMT2A (0.58) | KMT2AMEN1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL9457556 | 0.77 | BCAT2 (0.62) | KMT2AMEN1CYP1A2CYP3A4CYP2C9 | |
| Aklomide SCHEMBL29637033 | 0.77 | KMT2A (1.00) | KMT2AMEN1CYP1A2CYP3A4CYP2C9 | |
| Aklomide SCHEMBL328368 | 0.77 | KMT2A (1.00) | KMT2AMEN1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL7256623 | 0.77 | BCAT2 (0.57) | KMT2AMEN1SMN1; SMN2TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052617-A1 | REPROGRAMMING OF PLURIPOTENT STEM CELLS FOR IMPROVED CONTROL OF THEIR DIFFERENTIATION PATHWAYS | ETH Zurich (CH) | 2016-08-10 | — | — | EP | disclosed |
| WO-2015049342-A1 | REPROGRAMMING OF PLURIPOTENT STEM CELLS FOR IMPROVED CONTROL OF THEIR DIFFERENTIATION PATHWAYS | ETH ZURICH (CH) | 2015-04-09 | — | — | WO | disclosed |