Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17704660 | 0.93 | ALDH1A1 (0.58) | MEN1KMT2AALOX12TSHRALDH1A1 | |
| SCHEMBL10652958 | 0.88 | CES2 (0.53) | MEN1KMT2ATSHRALDH1A1CYP3A4 | |
| SCHEMBL10621310 | 0.88 | POLB (0.53) | MEN1KMT2AALOX12TSHRALDH1A1 | |
| SCHEMBL13239653 | 0.83 | VCAM1 (0.50) | MEN1KMT2ATSHRALDH1A1CYP3A4 | |
| SCHEMBL8295810 | 0.80 | ALDH1A1 (0.56) | MEN1KMT2AALOX12TSHRALDH1A1 | |
| SCHEMBL171914 | 0.79 | TSHR (0.72) | MEN1KMT2AALOX12TSHRALDH1A1 | |
| SCHEMBL29613904 | 0.79 | TSHR (0.72) | MEN1KMT2AALOX12TSHRALDH1A1 | |
| SCHEMBL715634 | 0.79 | ALDH1A1 (0.57) | MEN1KMT2AALOX12TSHRALDH1A1 | |
| SCHEMBL10662515 | 0.79 | ALDH1A1 (0.55) | MEN1KMT2AALOX12TSHRALDH1A1 | |
| SCHEMBL20707091 | 0.79 | ALDH1A1 (0.55) | MEN1KMT2AALOX12TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1150565-A1 | THIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | LION bioscience AG (DE) | 2001-11-07 | — | — | EP | claimed |
| WO-2000045635-A1 | THIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | LION BIOSCIENCE AG (DE) | 2000-08-10 | — | — | WO | claimed |
| US-8465889-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2013-06-18 | — | — | US | disclosed |
| US-8465889-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2013-06-18 | — | — | US | disclosed |
| US-8435706-B2 | — | — | 2013-05-07 | — | — | US | disclosed |
| US-8435706-B2 | — | — | 2013-05-07 | — | — | US | disclosed |
| US-20110268472-A1 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS | CANON KABUSHIKI KAISHA (JP) | 2011-11-03 | — | — | US | disclosed |
| US-20110268472-A1 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS | CANON KABUSHIKI KAISHA (JP) | 2011-11-03 | — | — | US | disclosed |