Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 6/20 | 0.47 |
| ▸ | AGTR2 | P50052 | 4/20 | 0.47 |
| ▸ | GP6 | Q9HCN6 | 1/20 | 0.45 |
| ▸ | MME | P08473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9154122 | 0.87 | AGTR1 (0.46) | AGTR1AGTR2GP6MME | |
| SCHEMBL8976726 | 0.82 | AGTR1 (0.48) | AGTR1AGTR2GP6 | |
| SCHEMBL8976721 | 0.82 | AGTR1 (0.48) | AGTR1AGTR2GP6 | |
| SCHEMBL8976717 | 0.82 | AGTR1 (0.48) | AGTR1AGTR2GP6 | |
| SCHEMBL9136944 | 0.80 | GP6 (0.58) | AGTR1AGTR2GP6 | |
| SCHEMBL7839432 | 0.78 | GP6 (0.51) | AGTR1AGTR2GP6 | |
| SCHEMBL3872489 | 0.78 | GP6 (0.66) | AGTR1AGTR2GP6 | |
| SCHEMBL7839994 | 0.76 | AGTR1 (0.56) | AGTR1AGTR2GP6 | |
| SCHEMBL9092277 | 0.75 | AGTR1 (0.56) | AGTR1AGTR2GP6 | |
| SCHEMBL9284564 | 0.74 | AGTR1 (0.46) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0513533-B1 | Heterocyclic substituted phenylacetic-acid derivatives, process for their preparation and their pharmaceutical application | BAYER AG (DE) | 2001-11-21 | — | — | EP | disclosed |
| EP-1127880-A2 | Phenylacetic acid derivatives substituted by a heterocycle and their use as A-II antagonists and as inhibitors of smooth muscle cell proliferation | BAYER AG (DE) | 2001-08-29 | — | — | EP | disclosed |
| US-5776964-A | HYPOTENSIVE AGENTS; ANTICHOLESTEROL AGENTS; CARDIOVASCULAR DISORDERS | BAYER AKTIENGESELLSCHAFT (DE) | 1998-07-07 | — | — | US | disclosed |
| US-5521206-A | HYPOTENSIVE AGENTS, TREATMENT OF ATHEROSCLEROSIS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-05-28 | — | — | US | disclosed |
| EP-0513533-A2 | Heterocyclic substituted phenylacetic-acid derivatives, process for their preparation and their pharmaceutical application | BAYER AG (DE) | 1992-11-19 | — | — | EP | disclosed |