Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 6/20 | 0.48 |
| ▸ | AGTR2 | P50052 | 5/20 | 0.48 |
| ▸ | GP6 | Q9HCN6 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8976726 | 1.00 | AGTR1 (0.48) | AGTR1AGTR2GP6 | |
| SCHEMBL8976721 | 1.00 | AGTR1 (0.48) | AGTR1AGTR2GP6 | |
| SCHEMBL8976549 | 0.87 | AGTR1 (0.50) | AGTR1AGTR2 | |
| SCHEMBL8976538 | 0.87 | AGTR1 (0.50) | AGTR1AGTR2 | |
| SCHEMBL8976534 | 0.87 | AGTR1 (0.50) | AGTR1AGTR2 | |
| SCHEMBL7842290 | 0.82 | AGTR1 (0.47) | AGTR1AGTR2GP6 | |
| SCHEMBL9136944 | 0.81 | GP6 (0.58) | AGTR1AGTR2GP6 | |
| SCHEMBL9154122 | 0.81 | AGTR1 (0.46) | AGTR1AGTR2GP6 | |
| SCHEMBL3872489 | 0.79 | GP6 (0.66) | AGTR1AGTR2GP6 | |
| SCHEMBL9422649 | 0.77 | AGTR1 (0.57) | AGTR1AGTR2GP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5508299-A | ANGIOTENSIN CONVERTING ENZYME INHIBITOR, ARTERIAL HYPOTENSIVE AGENT; CARDIOVASCULAR DISORDERS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-04-16 | — | — | US | disclosed |