Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 5/20 | 0.38 |
| ▸ | RAB9A | P51151 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 8/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7849728 | 0.85 | NUDT1 (0.33) | — | |
| SCHEMBL8105852 | 0.81 | CA12 (0.35) | NPC1RAB9AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL10749665 | 0.76 | PDE10A (0.36) | PIK3CGNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL1742675 | 0.75 | LMNA (0.53) | NPC1RAB9AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL15473325 | 0.74 | PIK3CG (0.46) | PIK3CGNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL259933 | 0.71 | PDE10A (0.46) | PIK3CGNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL7851412 | 0.71 | KDM4E (0.39) | PIK3CGNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL9593956 | 0.71 | MEN1 (0.40) | NPC1RAB9AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL8025547 | 0.71 | KDM4E (0.35) | PIK3CGNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL8902874 | 0.71 | SMN1; SMN2 (0.41) | NPC1RAB9AKDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0717743-B1 | N-ARYL 1,2,4]TRIAZOLO 1,5-a]PYRIDINE-2-SULFONAMIDE HERBICIDES | DOW AGROSCIENCES LLC (US) | 2001-11-14 | — | — | EP | disclosed |
| EP-0972774-A2 | 2-Benzylthio-8-amino(1,2,4)triazolo(1,5-pyridines | Dow AgroSciences LLC (US) | 2000-01-19 | — | — | EP | disclosed |
| US-5571775-A | EFFECTIVE ON A BROAD SPECTRUM OF VEGETATION AT LOW APPLICATION RATES | DOWELANCO (US) | 1996-11-05 | — | — | US | disclosed |
| WO-1996001826-A1 | N-ARYL[1,2,4]TRIAZOLO[1,5-a]PYRIDINE-2-SULFONAMIDE HERBICIDES | DOWELANCO (US) | 1996-01-25 | — | — | WO | disclosed |